Table of Contents  
Year : 2013  |  Volume : 4  |  Issue : 4  |  Page : 303-306  

How to calculate sample size in animal studies?

Department of Pharmacology, GMERS Medical College, Patan, Government Medical College, Surat, Gujarat, India

Date of Web Publication10-Oct-2013

Correspondence Address:
Jaykaran Charan
Department of Pharmacology, Government Medical College, Surat, Gujarat
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0976-500X.119726

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Calculation of sample size is one of the important component of design of any research including animal studies. If a researcher select less number of animals it may lead to missing of any significant difference even if it exist in population and if more number of animals selected then it may lead to unnecessary wastage of resources and may lead to ethical issues. In this article, on the basis of review of literature done by us we suggested few methods of sample size calculations for animal studies.

Keywords: Alpha error, animal studies, power, sample size

How to cite this article:
Charan J, Kantharia N D. How to calculate sample size in animal studies?. J Pharmacol Pharmacother 2013;4:303-6

How to cite this URL:
Charan J, Kantharia N D. How to calculate sample size in animal studies?. J Pharmacol Pharmacother [serial online] 2013 [cited 2021 Dec 7];4:303-6. Available from:

How many animals I should use for my study? This is one of the most confusing questions faced by a researcher. Too small sample size can miss the real effect in experiment and too large sample size will lead to unnecessary wasting of the resources and animals. [1] Issue of sample size has been highlighted adequately for the clinical trials and clinical studies, but not explored much in the case of animal studies in published literature. It is very important to teach young researchers and post-graduate students regarding importance and methods of sample size calculation. To clarify this issue of sample size in animal studies, we decided to search various articles available regarding the sample size in animal studies. We did PubMed search by using various MeSH terms such as "sample size," "sample size calculations," "animal studies" etc., and their combinations. We have also searched various articles through Google and Google Scholar. We have also searched various websites related to animal research (http://www.,, and-guidelines/sample-size-calculations/, First author read all available literature and an understanding about the concept is made in consultation with the second author. Here, we are explaining briefly about the method of sample size calculations in animal studies based on review of the literature carried out by us.

Basically, there are two methods of sample size calculation in animal studies. The most favored and most scientific method is calculation of sample size by power analysis. [2] Every effort should be carried out to calculate sample size by this method. This method is similar to the method used for calculation of sample size for clinical trials and clinical studies. Simple calculation can be carried out manually with the help of some formula [Appendix 1], but for complex calculations statistical software can be used or help from a statistician can be sought. To calculate the sample size by power analysis a researcher must have knowledge and information about these concepts:

  • Effect size: This is the difference between the mean of two groups (quantitative data) or proportions of events in two groups (qualitative data). A researcher should decide before the start of the study that how much minimum difference between two groups can be considered as clinically significant. The idea about clinically significant difference between the groups should be taken preferably from previously published studies [2],[3],[4],[5]
  • Standard deviation: Standard deviation measures variability within the sample. Information about standard deviation is needed only in the case of quantitative variables. Information about the standard deviation of a particular variable can be taken from previously published studies. If no such study is available then author should conduct a pilot study first and standard deviation can be calculated from the pilot study [2],[3],[4],[5]
  • Type 1 error: This is measured by significance level, which is usually fixed at the level of 5% (P = 0.05). This is an arbitrary value and can be decreased or increased according to the research question [2],[3],[4],[5]
  • Power: Power of a study is probability of finding an effect, which the study is aimed to find. This may be kept between 80% to even 99% depending on research question, but usually, it is kept at 80% [2],[3],[4],[5]
  • Direction of effect (one tailed or two tailed): When a researcher wants to explore the effect of some intervention, the actual effect observed in sample may be in same direction as researcher thought or it may be just opposite to that. If researcher feels that effect may be in both directions then he should use two tailed test and if he has strong reason to believe for the effect to lie in one direction then he can use one tailed test. In animal research, two tailed tests are usually used [2]
  • Statistical tests: For sample size calculation, it is important to have an idea about statistical test, which is to be applied on data. For simple statistical tests such as Students t-test or Chi-square test, manual calculation based on formula can be carried out [Appendix], but for complex tests like ANOVA or non-parametric tests help of statistician or use of software is needed [2],[4]
  • Expected attrition or death of animals: Final sample size should be adjusted for expected attrition. Suppose a researcher is expecting 10% attrition then the sample size calculated by formula or software should be divided by 0.9 to get actual sample size. Suppose sample size calculated by software is 10 animals per group and researcher is expecting 10% attrition then his final sample size will be 11 animals per group (10/0.9 = 11.11). Similarly, for 20% attrition sample size should be divided by 0.8. [5] This can be explained in the form of structured formula i.e.,
Corrected sample size = Sample size/ (1− [% attrition/100])

We suggest use of freely downloadable software G Power (Faul, Erdfelder, Lang and Buchner, 2007) for sample size calculation. This software is equally good for sample size calculation for clinical trials also. This software can be used for simple as well as complex sample size calculations. [6] G Power can calculate sample size based on pre-designed effect size at small, medium, and large difference between the groups based on Cohen's principles. [7] Information about other freely available software and calculators for sample size calculation is given in Appendix 2. More complex sample size will need more sophisticated software such as "nQuery advisor" or "MINITAB."

Second method of calculation is a crude method based on law of diminishing return. This method is called "resource equation" method. [2],[8],[9] This method is used when it is not possible to assume about effect size, to get an idea about standard deviation as no previous findings are available or when multiple endpoints are measured or complex statistical procedure is used for analysis. This method can also be used in some exploratory studies where testing of hypothesis is not the primary aim, but researcher is interested only in finding any level of difference between groups.

According to this method a value "E" is measured, which is nothing but the degree of freedom of analysis of variance (ANOVA). The value of E should lie between 10 and 20. If E is less than 10 then adding more animals will increase the chance of getting more significant result, but if it is more than 20 then adding more animals will not increase the chance of getting significant results. Though, this method is based on ANOVA, it is applicable to all animal experiments. Any sample size, which keeps E between 10 and 20 should be considered as an adequate. E can be measured by following formula:

E = Total number of animals − Total number of groups

Suppose a researcher wants to see the effect of a drug and he made five groups (one group as control and four groups of different doses of that drug) with 10 rats each. In this case E will be

E = (10 × 5) − 5

E = 50 − 5 = 45, which is more than 20 hence sample size in this experiment is more than necessary. However, if sample size is five per group then E will be 20, which is the acceptable limit and hence can be considered as adequate sample size.

This method is easy, but it cannot be considered as robust as power analysis method.

We want to suggest researchers to include a statement about method of calculation of sample size and justification of sample size in the manuscript they want to publish. Animals in research: Reporting in vivo experiments guideline recommends inclusion of a statement mentioning justification of the sample size used in research and detail of method of calculation of sample size. [10] All components of sample size calculation such as effect size, type 1 and type 2 error, one tailed/two tailed test, standard deviation etc., should be reported in manuscript sent for publication the way it is suggested for the clinical research. [11] Shortage of resources (budget, manpower), time constrain etc., cannot be considered as valid justification regarding decision of sample size. Many researchers consider six animals per group as adequate sample size, but after reviewing available literature on this issue we came to a conclusion that this notion of six animals per group has little scientific and statistical basis. This is a brief description and readers are requested to read more resources available for better understanding of various concepts related to the sample size calculation in animal studies.

   Acknowledgment Top

We want to acknowledge unknown reviewer for constructive comments and guidance for improvisation of this manuscript.

   References Top

1.Fitts DA. Ethics and animal numbers: Informal analyses, uncertain sample sizes, inefficient replications, and type I errors. J Am Assoc Lab Anim Sci 2011;50:445-53.  Back to cited text no. 1
2.Festing MF, Altman DG. Guidelines for the design and statistical analysis of experiments using laboratory animals. ILAR J 2002;43:244-58.  Back to cited text no. 2
3.Lenth RV. Some practical guidelines for effective sample size determination. Am Stat 2001;55:187-93.  Back to cited text no. 3
4.Jones SR, Carley S, Harrison M. An introduction to power and sample size estimation. Emerg Med J 2003;20:453-8.  Back to cited text no. 4
5.Naduvilath TJ, John RK, Dandona L. Sample size for ophthalmology studies. Indian J Ophthalmol 2000;48:245-50.  Back to cited text no. 5
[PUBMED]  Medknow Journal  
6.Faul F, Erdfelder E, Lang AG, Buchner A. G*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods 2007;39:175-91.  Back to cited text no. 6
7.Cohen J. Statistical Power Analysis for the Behavioral Sciences. 2 nd ed. Hillsdale, NJ: Lawrence Erlbaum; 1988.  Back to cited text no. 7
8.National centre for replacement, refinement, and reduction animals in research. Experimental design/statistics. [about 2 screen] Available from: [Last cited on 2012 Nov 02].  Back to cited text no. 8
9.Festing MF. Design and statistical methods in studies using animal models of development. ILAR J 2006;47:5-14.  Back to cited text no. 9
10.Kilkenny C, Browne WJ, Cuthill IC, Emerson M, Altman DG. Improving bioscience research reporting: The ARRIVE guidelines for reporting animal research. J Pharmacol Pharmacother 2010;1:94-9.  Back to cited text no. 10
[PUBMED]  Medknow Journal  
11.Jaykaran P, Yadav N, Chavda, Kantharia ND. Some issues related to the reporting of statistics in clinical trials published in Indian Medical Journals: A survey. Int J Pharmacol 2010;6:354-9.  Back to cited text no. 11

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Nahed Abdel-Aziz, Sawsan M. El-Sonbaty, Marwa G. A. Hegazy
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51 Protective effects of propolis extract against nicotine-evoked pulmonary and hepatic damage
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Environmental Science and Pollution Research. 2021;
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52 Zinc Supplementation During Pregnancy Alleviates Lipopolysaccharide-Induced Glial Activation and Inflammatory Markers Expression in a Rat Model of Maternal Immune Activation
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53 Characterization of a xenograft model for anti-CD19 CAR T cell studies
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Clinical and Translational Oncology. 2021; 23(10): 2181
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54 Targeting the RNA-Binding Protein HuR Alleviates Neuroinflammation in Experimental Autoimmune Encephalomyelitis: Potential Therapy for Multiple Sclerosis
Vittoria Borgonetti, Maria Domenica Sanna, Laura Lucarini, Nicoletta Galeotti
Neurotherapeutics. 2021; 18(1): 412
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55 LncRNA TUG1 regulates the balance of HuR and miR-29b-3p and inhibits intestinal epithelial cell apoptosis in a mouse model of ulcerative colitis
Yuxi Tian, Ying Wang, Fujun Li, Junwen Yang, Yan Xu, Miao Ouyang
Human Cell. 2021; 34(1): 37
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56 Human Dental Pulp Stem Cells (DPSCs) Therapy in Rescuing Photoreceptors and Establishing a Sodium Iodate-Induced Retinal Degeneration Rat Model
Chenshen Lam, Hiba Amer Alsaeedi, Avin Ee-Hwan Koh, Mohd Hairul Nizam Harun, Angela Ng Min Hwei, Pooi Ling Mok, Chi D Luu, Then Kong Yong, Suresh Kumar Subbiah, Mae-Lynn Catherine Bastion
Tissue Engineering and Regenerative Medicine. 2021; 18(1): 143
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57 Influence of mini-screw implant-assisted intrusion on orthodontically induced inflammatory root resorption: a systematic review
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European Archives of Paediatric Dentistry. 2021; 22(3): 341
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58 Cytotoxicity of Novel Polymeric Gel Matrix Triple Antibiotic Paste—an In Vitro Study
Prasanna T. Dahake, Sudhindra M. Baliga, Vijay M. Kumbar, Kishore G. Bhat
Regenerative Engineering and Translational Medicine. 2021; 7(1): 21
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59 Antimicrobial peptides for the prevention and treatment of dental caries: A concise review
John Yun Niu, Iris Xiaoxue Yin, William Ka Kei Wu, Quan-Li Li, May Lei Mei, Chun Hung Chu
Archives of Oral Biology. 2021; 122: 105022
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60 Hippocampal silent infarct leads to subtle cognitive decline that is associated with inflammation and gliosis at twenty-four hours after injury in a rat model
Caitlin A. Finney, Margaret J. Morris, R. Frederick Westbrook, Nicole M. Jones
Behavioural Brain Research. 2021; 401: 113089
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61 Oxygen generating scaffolds regenerate critical size bone defects
Sanika Suvarnapathaki, Xinchen Wu, Tengfei Zhang, Michelle A. Nguyen, Anastasia A. Goulopoulos, Bin Wu, Gulden Camci-Unal
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62 Matrix metalloproteinase (MMP)-degradable tissue engineered periosteum coordinates allograft healing via early stage recruitment and support of host neurovasculature
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63 Prevention and reversal of ketamine-induced experimental psychosis in mice by the neuroactive flavonoid, hesperidin: The role of oxidative and cholinergic mechanisms
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64 High Fructose Drives the Serine Synthesis Pathway in Acute Myeloid Leukemic Cells
Sangmoo Jeong, Angela Maria Savino, Rachel Chirayil, Ersilia Barin, Yuanming Cheng, Sun-Mi Park, Alexandra Schurer, Edouard Mullarky, Lewis C. Cantley, Michael G. Kharas, Kayvan R. Keshari
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65 Impact of vaginal distention on cell senescence in an animal model of pelvic organ prolapse
Adam M. Hare, Neha G. Gaddam, Haolin Shi, Jesus F. Acevedo, R. Ann Word, Maria E. Florian-Rodriguez
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66 Not all mice are alike: Mixed-strain housing alters social behaviour
Carina Bodden, Maximilian Wewer, Niklas Kästner, Rupert Palme, Sylvia Kaiser, Norbert Sachser, S. Helene Richter
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67 Tamoxifen offers long-term neuroprotection after hippocampal silent infarct in male rats
Caitlin A. Finney, Artur Shvetcov, R. Frederick Westbrook, Margaret J. Morris, Nicole M. Jones
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68 Microglial vesicles improve post-stroke recovery by preventing immune cell senescence and favoring oligodendrogenesis
Stefano Raffaele, Paolo Gelosa, Elisabetta Bonfanti, Marta Lombardi, Laura Castiglioni, Mauro Cimino, Luigi Sironi, Maria P. Abbracchio, Claudia Verderio, Marta Fumagalli
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69 Protein malnutrition early in life increased apoptosis but did not alter the ß-cell mass during gestation
Daniela de Souza Vial-Dahmer, Chaiane Aline da Rosa-Santos, Luana Resende Silva, Vanessa Cristina Arantes, Marise Auxiliadora de Barros Reis, Marciane Milanski, Egberto Gaspar de Moura, Patrícia Cristina Lisboa, Everardo Magalhães Carneiro, Amílcar Sabino Damazo, Márcia Queiroz Latorraca
British Journal of Nutrition. 2021; 125(10): 1111
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70 Ameliorative effect of enhanced Fischer ratio flaxseed protein hydrolysate in combination with antioxidant micronutrients on ethanol-induced hepatic damage in a rat model
Nida Ume Salma, K. Govindaraju, Belur Shivappa Gnanesh Kumar, S.P. Muthukumar, A. Jyothi Lakshmi
British Journal of Nutrition. 2021; : 1
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71 Neonatal zingerone protects against the development of high-fructose diet-induced metabolic syndrome in adult Sprague-Dawley rats
N. Muhammad, B. W. Lembede, K. H Erlwanger
Journal of Developmental Origins of Health and Disease. 2021; 12(4): 671
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72 Maternal soy protein isolate diet during lactation programs deleterious effects on hepatic lipid metabolism, atherogenic indices, and function of adrenal in adult rat offspring
Maíra Schuchter Ferreira, Sheila Cristina Potente Dutra Luquetti, Poliana Guiomar de Almeida Brasiel, Kacia Mateus, Alice Helena de Souza Paulino, Mayara Medeiros de Freitas Carvalho, Ana Eliza Andreazzi, Aline Silva de Aguiar
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73 Multifunctional 3D-Printed Wound Dressings
Moien Alizadehgiashi, Carine R. Nemr, Mahshid Chekini, Daniel Pinto Ramos, Nitesh Mittal, Sharif U. Ahmed, Nancy Khuu, Shana O. Kelley, Eugenia Kumacheva
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74 N-Adamantyl Phthalimidine: A New Thalidomide-like Drug That Lacks Cereblon Binding and Mitigates Neuronal and Synaptic Loss, Neuroinflammation, and Behavioral Deficits in Traumatic Brain Injury and LPS Challenge
Shih Chang Hsueh, Weiming Luo, David Tweedie, Dong Seok Kim, Yu Kyung Kim, Inho Hwang, Jung-Eun Gil, Baek-Soo Han, Yung-Hsiao Chiang, Warren Selman, Barry J. Hoffer, Nigel H. Greig
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75 E47 upregulates ?Np63a to promote growth of squamous cell carcinoma
Jing Xu, Fengtian Li, Ya Gao, Rongtian Guo, Liangping Ding, Mengyuan Fu, Yong Yi, Hu Chen, Zhi-Xiong Jim Xiao, Mengmeng Niu
Cell Death & Disease. 2021; 12(4)
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76 TRPV1 alleviates osteoarthritis by inhibiting M1 macrophage polarization via Ca2+/CaMKII/Nrf2 signaling pathway
Zhongyang Lv, Xingquan Xu, Ziying Sun, Yannick Xiaofan Yang, Hu Guo, Jiawei Li, Kuoyang Sun, Rui Wu, Jia Xu, Qing Jiang, Shiro Ikegawa, Dongquan Shi
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77 Western diet leads to aging-related tumorigenesis via activation of the inflammatory, UPR, and EMT pathways
Ricardo Imbroisi Filho, Alan C. Ochioni, Amanda M. Esteves, João G. B. Leandro, Thainá M. Demaria, Mauro Sola-Penna, Patricia Zancan
Cell Death & Disease. 2021; 12(7)
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78 IGF-1R is a molecular determinant for response to p53 reactivation therapy in conjunctival melanoma
Dawei Song, Sonia Cismas, Caitrin Crudden, Eric Trocme, Claire Worrall, Naida Suleymanova, Tingting Lin, Huiyuan Zheng, Stefan Seregard, Ada Girnita, Leonard Girnita
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79 Protective effects of growth hormone-releasing hormone analogs in DSS-induced colitis in mice
Lucia Recinella, Annalisa Chiavaroli, Valentina Di Valerio, Serena Veschi, Giustino Orlando, Claudio Ferrante, Iacopo Gesmundo, Riccarda Granata, Renzhi Cai, Wei Sha, Andrew V. Schally, Rossano Lattanzio, Luigi Brunetti, Sheila Leone
Scientific Reports. 2021; 11(1)
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80 nAChRs gene expression and neuroinflammation in APPswe/PS1dE9 transgenic mouse
Chiara D’Angelo, Erica Costantini, Nieves Salvador, Michele Marchioni, Marta Di Nicola, Nigel H. Greig, Marcella Reale
Scientific Reports. 2021; 11(1)
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81 Repeatability, reproducibility, and agreement of three tonometers for measuring intraocular pressure in rabbits
Christian J. F. Bertens, Ralph J. S. van Mechelen, Tos T. J. M. Berendschot, Marlies Gijs, Jarno E. J. Wolters, Theo G. M. F. Gorgels, Rudy M. M. A. Nuijts, Henny J. M. Beckers
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82 Sample Size Calculation in Medical Research: A Primer
Jaykaran Charan, Rimplejeet Kaur, Pankaj Bhardwaj, Kuldeep Singh, Sneha R. Ambwani, Sanjeev Misra
Annals of the National Academy of Medical Sciences (India). 2021; 57(02): 074
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83 A Study on the Effect of Valeric Acid in Alzheimer's Induced Rats by the Estimation of Aß 1-42 Biomarker
Blessina Sugandhi Dulla, Bindhu S., Leena Pramod K.
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84 Dose-dependent long-term effects of a single radiation event on behaviour and glial cells
Marie-Claire Ung, Lillian Garrett, Claudia Dalke, Valentin Leitner, Daniel Dragosa, Daniela Hladik, Frauke Neff, Florian Wagner, Horst Zitzelsberger, Gregor Miller, Martin Hrabe de Angelis, Ute Rößler, Daniela Vogt Weisenhorn, Wolfgang Wurst, Jochen Graw, Sabine M. Hölter
International Journal of Radiation Biology. 2021; 97(2): 156
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85 Enhanced viability and function of mesenchymal stromal cell spheroids is mediated via autophagy induction
Shobha Regmi, Pawan Kumar Raut, Shiva Pathak, Prakash Shrestha, Pil-Hoon Park, Jee-Heon Jeong
Autophagy. 2021; 17(10): 2991
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86 The Effect of Pluchea indica (L.) Less. Tea on Blood Glucose and Lipid Profile in People with Prediabetes: A Randomized Clinical Trial
Kittipot Sirichaiwetchakoon, Seekaow Churproong, Sajeera Kupittayanant, Griangsak Eumkeb
The Journal of Alternative and Complementary Medicine. 2021; 27(8): 669
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87 Effect of Rubus idaeus L. Consumption During Pregnancy on Maternal Mice and Their Offspring
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Journal of Medicinal Food. 2021;
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88 Positive Effects of Melatonin on Renal Nitric Oxide-Asymmetric Dimethylarginine Metabolism in Fructose-Fed Rats
Ozge Tugce Pasaoglu, Filiz Sezen Bircan, Turgut Topal, Nurten Turkozkan
Metabolic Syndrome and Related Disorders. 2021; 19(3): 120
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89 A honokiol-enriched Magnolia officinalis Rehder & E.H. Wilson. bark extract possesses anxiolytic-like activity with neuroprotective effect through the modulation of CB1 receptor
Vittoria Borgonetti, Paolo Governa, Fabrizio Manetti, Elisabetta Miraldi, Marco Biagi, Nicoletta Galeotti
Journal of Pharmacy and Pharmacology. 2021; 73(9): 1161
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90 Experimental design of preclinical experiments: number of PDX lines vs subsampling within PDX lines
Jeanette E Eckel-Passow, Gaspar J Kitange, Paul A Decker, Matthew L Kosel, Danielle M Burgenske, Ann L Oberg, Jann N Sarkaria
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91 Growth indices, intestinal histomorphology, and blood profile of rabbits fed probiotics- and prebiotics-supplemented diets
Chinwe Uchechi Nwachukwu, Karimat Imam Aliyu, Emmanuel Olubisi Ewuola
Translational Animal Science. 2021; 5(3)
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92 Moderate aerobic exercise training ameliorates impairment of mitochondrial function and dynamics in skeletal muscle of high-fat diet-induced obese mice
Jun-Won Heo, Mi-Hyun No, Jinkyung Cho, Youngju Choi, Eun-Jeong Cho, Dong-Ho Park, Tae-Woon Kim, Chang-Ju Kim, Dae Yun Seo, Jin Han, Young C. Jang, Su-Jeen Jung, Ju-Hee Kang, Hyo-Bum Kwak
The FASEB Journal. 2021; 35(2)
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93 Intranasal delivery of an antisense oligonucleotide to the RNA-binding protein HuR relieves nerve injury-induced neuropathic pain
Vittoria Borgonetti, Nicoletta Galeotti
Pain. 2021; 162(5): 1500
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94 The effect of calorie restricted diet on anthropometric and biochemical parameters in Sprague Dawley rats
Muhammad Fakhruddin Irfan Sazali, Maleeka Abdullah Hilmy, Norshafarina Shari, Lilik Herawati, Nurul Izza Nordin, Zulhabri Othman
Nutrition & Food Science . 2021; 51(8): 1177
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95 Association between age-related macular degeneration and periodontal and peri-implant diseases: a systematic review
Fawad Javed, Anton Sculean, Georgios E. Romanos
Acta Ophthalmologica. 2021; 99(4): 351
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96 Evaluation of the neuroprotective effect of donepezil in type 2 diabetic rats
Adel A. Gomaa, Rania M. Makboul, Mohamed A. El-Mokhtar, Engy A. Abdel-Rahman, Esraa A. Ahmed, Mariam A. Nicola
Fundamental & Clinical Pharmacology. 2021; 35(1): 97
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97 The HIV reverse transcriptase Inhibitor Tenofovir suppressed DMH/HFD-induced colorectal cancer in Wistar rats
Dana A. Sherif, Mirhan N. Makled, Ghada M. Suddek
Fundamental & Clinical Pharmacology. 2021; 35(6): 940
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98 Human amniotic fluid stem cells can improve cerebral vascular remodelling and neurological function after focal cerebral ischaemia in diabetic rats
Ching-Chung Liang, Steven W. Shaw, Yung-Hsin Huang, Tsong-Hai Lee
Journal of Cellular and Molecular Medicine. 2021; 25(21): 10185
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99 Effect of chain length and saturation of the fatty acids in dietary triglycerides on lipid metabolism in Wistar rats
Chathuri M. Senanayake, Harsha Hapugaswatta, Gangi R. Samarawickrama, Nimanthi Jayathilaka, Kapila N. Seneviratne
Journal of Food Biochemistry. 2021; 45(4)
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100 Receptor for advanced glycation end products up-regulation in cerebral endothelial cells mediates cerebrovascular-related amyloid ß accumulation after Porphyromonas gingivalis infection
Fan Zeng, Yicong Liu, Wanyi Huang, Hong Qing, Tomoko Kadowaki, Haruhiko Kashiwazaki, Junjun Ni, Zhou Wu
Journal of Neurochemistry. 2021; 158(3): 724
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101 Examination of genetic and pharmacological tools to study the proteasomal deubiquitinating enzyme ubiquitin-specific protease 14 in the nervous system
Tina Tian, John W. McLean, Julie A. Wilson, Scott M. Wilson
Journal of Neurochemistry. 2021; 156(3): 309
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102 The metabolite GLP-1 (9-36) is neuroprotective and anti-inflammatory in cellular models of neurodegeneration
Yazhou Li, Elliot J. Glotfelty, Tobias Karlsson, Lowella V. Fortuno, Brandon K. Harvey, Nigel H. Greig
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103 Early maternal separation enhances melanoma progression in adult female mice by immune mechanisms
Francisco Stefânio Barreto, Wesley Lyeverton Correia Ribeiro, Bruno Coêlho Cavalcanti, Paulo Goberlânio de Barros Silva, Caren Nádia Soares de Sousa, Germana Silva Vasconcelos, Ana Paula Negreiros Nunes, Manoel Odorico de Moraes Filho, Danielle S. Macedo
Annals of the New York Academy of Sciences. 2021; 1502(1): 40
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104 Influence of thyroxine supplementation on orthodontically induced tooth movement and/or inflammatory root resorption: A systematic review
Stefani Berry, Fawad Javed, Paul Emile Rossouw, Abdul Basir Barmak, Eleni-Marina Kalogirou, Dimitrios Michelogiannakis
Orthodontics & Craniofacial Research. 2021; 24(2): 206
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105 ‘SMASH’ recommendations for standardised microscopic arthritis scoring of histological sections from inflammatory arthritis animal models
Silvia Hayer, Margriet J Vervoordeldonk, Maria C Denis, Marietta Armaka, Markus Hoffmann, Johan Bäcklund, Kutty Selva Nandakumar, Birgit Niederreiter, Christina Geka, Anita Fischer, Nina Woodworth, Stephan Blüml, George Kollias, Rikard Holmdahl, Florence Apparailly, Marije I Koenders
Annals of the Rheumatic Diseases. 2021; 80(6): 714
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106 Angelica dahurica and Rheum officinale Facilitated Diabetic Wound Healing by Elevating Vascular Endothelial Growth Factor
Yuh-Huey Chao, Wan-Ting Yang, Ming-Chang Li, Fwu-Lin Yang, Ru-Ping Lee
The American Journal of Chinese Medicine. 2021; 49(06): 1515
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107 Guidelines for the measurement of vascular function and structure in isolated arteries and veins
Camilla F. Wenceslau, Cameron G. McCarthy, Scott Earley, Sarah K. England, Jessica A. Filosa, Styliani Goulopoulou, David D. Gutterman, Brant E. Isakson, Nancy L. Kanagy, Luis A. Martinez-Lemus, Swapnil K. Sonkusare, Pratish Thakore, Aaron J. Trask, Stephanie W. Watts, R. Clinton Webb
American Journal of Physiology-Heart and Circulatory Physiology. 2021; 321(1): H77
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108 Evaluation of the Obesity Prevention, Blood Glucose, and Blood Lipid Control of Vietnamese Rice Varieties in High-Fat Diet-Induced Obese Mice
Thuy Linh Nguyen, Khanh Son Trinh, Zheng-Fei Yan
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109 The Therapeutic Potential of Inflamed Gingiva-Derived Mesenchymal Stem Cells in Preclinical Studies: A Scoping Review of a Unique Biomedical Waste
Gamilah Al-Qadhi, Sarah Al-Rai, Layla Hafed, Manuel Scimeca
Stem Cells International. 2021; 2021: 1
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110 The Effect of TISSEELTM on Confined Bowel Perforation: An Experimental Study
Maximos Frountzas, Vasilios Pergialiotis, Konstantinos Stergios, Christina Nikolaou, Patroklos Katafygiotis, Andreas C. Lazaris, Dimitrios Schizas, Despina N. Perrea, Nikolaos Nikiteas, Konstantinos G. Toutouzas
European Surgical Research. 2021; : 1
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111 Sample size, power and effect size revisited: simplified and practical approaches in pre-clinical, clinical and laboratory studies
Ceyhan Ceran Serdar, Murat Cihan, Dogan Yücel, Muhittin A Serdar
Biochemia medica. 2021; 31(1): 27
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112 Comparative effect of dense-and-disperse versus non-repetitive and non-sequential frequencies in electroacupuncture-induced analgesia in a rodent model of peripheral neuropathic pain
Liaw Chao, Alexandre SR Gonçalves, Ana Carolina P Campos, Daniele V Assis, Rodrigo Jerônimo, Mayra A Kuroki, Fernando M Sant’Anna, Yunsan Meas, Yves Rouxeville, Wu Hsing, Rosana L Pagano
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113 Development of a Chronic Canine Ovariohysterectomy Model to Evaluate Vaginal Cuff Healing Using Two Closure Systems
David Wiseman, Josa A. Hanzlik, James A. Richardson, John M. Shelton, Bret M. Evers, Michael P. Diamond, Ryan Brown, Dan C. Mazzucco
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114 Anti-Hyperuricemic and Uricosuric Potential of Berberis vulgaris in Oxonate-Induced Hyperuricemic Rats
Muhammad Bilal, Saeed Ahmad, Tayyeba Rehman, Aymen Owais Ghauri, Sana Khalid, Waheed Mumtaz Abbasi, Shahbaz Ahmad Zakki
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115 Curative role of mesenchymal stromal cells in chronic pancreatitis: Modulation of MAPK and TGF-ß1/SMAD factors
Hager S Taha, Enas M Moustafa, Fatma SM Moawed, Marwa GA Hegazy
International Journal of Immunopathology and Pharmacology. 2021; 35: 2058738421
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116 Annona muricata Linn and Khaya grandifoliola C.DC. Reduce Oxidative Stress In Vitro and Ameliorate Plasmodium berghei-Induced Parasitemia and Cytokines in BALB/c Mice
Hope Onohuean, Abdullateef I. Alagbonsi, Ibe M. Usman, Keneth Iceland Kasozi, Athanasios Alexiou, Reem H. Badr, Gaber El-Saber Batiha, Joseph O. C. Ezeonwumelu
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117 Vaping-induced metabolomic signatures in the circulation of mice are driven by device type, e-liquid, exposure duration and sex
Alexander Moshensky, Mulong Du, John Shin, Ira Advani, Deepti Gunge, Denzil Mathew, Rita Alkolla, Ashley Du, Christian Javier, Lauren Ma, Albert Tran, Nicholas Nguyen, Jarod Olay, Sedtavut Nilaad, Jeffrey Ding, Mahan Najhawan, Jeramie D. Watrous, Christine M. Bojanowksi, Mohit Jain, David C. Christiani, Laura E. Crotty Alexander
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118 Prevalence of commonly diagnosed disorders in UK dogs under primary veterinary care: results and applications
Dan G. O’Neill, Hannah James, Dave C. Brodbelt, David B. Church, Camilla Pegram
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119 A novel surgical model for the preclinical assessment of the osseointegration of dental implants: a surgical protocol and pilot study results
Noura M. AlOtaibi, Michael Dunne, Ashraf F. Ayoub, Kurt B. Naudi
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120 Qualitative ultrastructural analysis of the submandibular salivary glands after administration of khat: in vivo study
Gamilah Al-Qadhi, Rabab Mubarak
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121 Hypoxic mesenchymal stem cells ameliorate acute kidney ischemia-reperfusion injury via enhancing renal tubular autophagy
Wei-Cheng Tseng, Pei-Ying Lee, Ming-Tsun Tsai, Fu-Pang Chang, Nien-Jung Chen, Chiang-Ting Chien, Shih-Chieh Hung, Der-Cherng Tarng
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122 Induced pluripotent stem cells can improve thrombolytic effect of low-dose rt-PA after acute carotid thrombosis in rat
Hsi-Lung Hsieh, Ching-Chung Liang, Cheng-You Lu, Jen-Tsung Yang, Chiu-Yen Chung, Yu-Shien Ko, Tsong-Hai Lee
Stem Cell Research & Therapy. 2021; 12(1)
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123 Human dental pulp stem cells attenuate streptozotocin-induced parotid gland injury in rats
Rasha H. Al-Serwi, Ahmed Othman Fathy Othman El-Kersh, Gehan El-Akabawy
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124 Feasibility of a specific task-oriented training versus its combination with manual therapy on balance and mobility in people post stroke at the chronic stage: study protocol for a pilot randomised controlled trial
Kristina Traxler, Franz Schinabeck, Eva Baum, Edith Klotz, Barbara Seebacher
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125 Cannabis sativa and/or melatonin do not alter brain lipid but alter oxidative mechanisms in female rats
Halimat Amin Abdulrahim, Isiaka Abdullateef Alagbonsi, Oluwasola Amuda, Noah Adavize Omeiza, Abdul-Rahuf Aderemi Feyitimi, Luqman Aribidesi Olayaki
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126 The fertility assessment of normal cyclic Wistar rats following the administration of methanolic extract of Portulaca oleracea: an experimental study
Izuchukwu Azuka Okafor, Uchenna Somtochukwu Nnamah, Jude Nnaka
Middle East Fertility Society Journal. 2021; 26(1)
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127 TDP-43 mislocalization drives neurofilament changes in a novel model of TDP-43 proteinopathy
Rachel Atkinson, Jacqueline Leung, James Bender, Matthew Kirkcaldie, James Vickers, Anna King
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128 Isolation and primary culture of Galleria mellonella hemocytes for infection studies
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129 Chalcones identify cTXNPx as a potential antileishmanial drug target
Douglas O. Escrivani, Rebecca L. Charlton, Marjolly B. Caruso, Gabriela A. Burle-Caldas, Maria Paula G. Borsodi, Russolina B. Zingali, Marcos V. Palmeira-Mello, Jéssica B. de Jesus, Alessandra M. T. Souza, Bárbara Abrahim-Vieira, Stefanie Freitag-Pohl, Ehmke Pohl, Paul W. Denny, Bartira Rossi-Bergmann, Patrick G. Steel, Tiago Donatelli Serafim
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Nazanin Majidi, Mahboubeh Kosari Monfared, Fatemeh Mazaheri-Eftekhar, Ariyo Movahedi, Majid Karandish
Journal of Complementary and Integrative Medicine. 2021; 0(0)
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131 Male castration increases adiposity via small intestinal microbial alterations
Tae Woong Whon, Hyun Sik Kim, Na-Ri Shin, Eun Sung Jung, Euon Jung Tak, Hojun Sung, Mi-Ja Jung, Yun-Seok Jeong, Dong-Wook Hyun, Pil Soo Kim, Yu Kyung Jang, Choong Hwan Lee, Jin-Woo Bae
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132 Alleviation of a polyglucosan storage disorder by enhancement of autophagic glycogen catabolism
Or Kakhlon, Hilla Vaknin, Kumudesh Mishra, Jeevitha D’Souza, Monzer Marisat, Uri Sprecher, Shane Wald-Altman, Anna Dukhovny, Yuval Raviv, Benny Da’adoosh, Hamutal Engel, Sandrine Benhamron, Keren Nitzan, Sahar Sweetat, Anna Permyakova, Anat Mordechai, Hasan Orhan Akman, Hanna Rosenmann, Alexander Lossos, Joseph Tam, Berge A. Minassian, Miguel Weil
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134 Antihyperglycemic effect and phytochemical investigation of Rubia cordifolia (Indian Madder) leaves extract
Muhammad Shafiq Khan, Shahid Aziz, Muhammad Zakryya Khan, Zafar Mahmood Khalid, Muhammad Riaz, Dawood Ahmed, Iftikhar Ali, Nazia Arif, Deiji Wang, Muhammad Sheeraz Ahmad, Nafeesa Zahid
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135 Short-Term Effects of Cell Phone Radiation on Fertility and Testosterone Hormone in Male Rats
Düzce Tip Fakültesi Dergisi. 2021;
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136 Engaging a polylactide copolymer in oral tissue regeneration: first validation of Suprathel® for guided epithelial and osseous healing
Sergiu Vacaras, Grigore Baciut, Dan Gheban, Simion Bran, Horatiu Colosi, Septimiu Toader, Daiana Opris, Winfried Kretschmer, Avram Manea, Gabriel Armencea, Mihaela Baciut, Horia Opris, Ileana Mitre, Mihaela Hedesiu, Cristian Dinu
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137 Predicting morbidity and mortality using automated milk feeders: A scoping review
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138 Effect of epidural polydeoxyribonucleotide in a rat model of lumbar foraminal stenosis
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The Korean Journal of Pain. 2021; 34(4): 394
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139 Intrauterine Gardnerella vaginalis Infection Results in Fetal Growth Restriction and Alveolar Septal Hypertrophy in a Rabbit Model
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140 Bifidobacterium Strains Present Distinct Effects on the Control of Alveolar Bone Loss in a Periodontitis Experimental Model
Natali Shimabukuro, Amália C. de S. Cataruci, Karin H. Ishikawa, Bruna E. de Oliveira, Dione Kawamoto, Ellen S. Ando-Suguimoto, Emmanuel Albuquerque-Souza, Jacques R. Nicoli, Caroline M. Ferreira, Jean de Lima, Manuela R. Bueno, Leandro B. R. da Silva, Pedro H. F. Silva, Michel R. Messora, Niels O. S. Camara, Maria Regina L. Simionato, Marcia P. A. Mayer
Frontiers in Pharmacology. 2021; 12
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141 Psychedelics and Neuroplasticity: A Systematic Review Unraveling the Biological Underpinnings of Psychedelics
Cato M. H. de Vos, Natasha L. Mason, Kim P. C. Kuypers
Frontiers in Psychiatry. 2021; 12
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142 Vaccination With Recombinant Adenoviruses Expressing the Bluetongue Virus Subunits VP7 and VP2 Provides Protection Against Heterologous Virus Challenge
José Manuel Rojas, Diego Barba-Moreno, Miguel Avia, Noemí Sevilla, Verónica Martín
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143 Effect of Reducing Ataxia-Telangiectasia Mutated (ATM) in Experimental Autosomal Dominant Polycystic Kidney Disease
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Cells. 2021; 10(3): 532
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144 Motor Cortex Stimulation Reversed Hypernociception, Increased Serotonin in Raphe Neurons, and Caused Inhibition of Spinal Astrocytes in a Parkinson’s Disease Rat Model
Ana Carolina P. Campos, Miriã B. Berzuíno, Gabriela R. Barbosa, Helena M. R. C. Freire, Patricia S. Lopes, Danielle V. Assis, Erich T. Fonoff, Rosana L. Pagano
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145 Lactobacillus ruminis Alleviates DSS-Induced Colitis by Inflammatory Cytokines and Gut Microbiota Modulation
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146 A Hyaluronan and Platelet-Rich Plasma Hydrogel for Mesenchymal Stem Cell Delivery in the Intervertebral Disc: An Organ Culture Study
Fabrizio Russo, Luca Ambrosio, Marianna Peroglio, Wei Guo, Sebastian Wangler, Jan Gewiess, Sibylle Grad, Mauro Alini, Rocco Papalia, Gianluca Vadalà, Vincenzo Denaro
International Journal of Molecular Sciences. 2021; 22(6): 2963
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147 Lipid Emulsion Enhances Vasoconstriction Induced by Dexmedetomidine in the Isolated Endothelium-Intact Aorta
Soo Hee Lee, Seong-Ho Ok, Seung Hyun Ahn, Hyun-Jin Kim, Sung Il Bae, Ji-Yoon Kim, Kyeong-Eon Park, Yeran Hwang, Ju-Tae Sohn
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148 Senolytic Therapy for Cerebral Ischemia-Reperfusion Injury
Songhyun Lim, Tae Jung Kim, Young-Ju Kim, Cheesue Kim, Sang-Bae Ko, Byung-Soo Kim
International Journal of Molecular Sciences. 2021; 22(21): 11967
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149 T Cell Peptides Derived from Invasive Stages of Schistosoma mansoni as Potential Schistosomiasis Vaccine
Julio López-Abán, Belén Vicente, Elías Kabbas-Piñango, Juan Hernández-Goenaga, Javier Sánchez-Montejo, María Aguiriano, Esther del Olmo, Magnolia Vanegas, Manuel Alfonso Patarroyo, Antonio Muro
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150 Bevacizumab Arrests Osteoarthritis Progression in a Rabbit Model: A Dose-Escalation Study
Gianluca Vadalà, Luca Ambrosio, Caterina Cattani, Roberta Bernardini, Antonino Giacalone, Rocco Papalia, Vincenzo Denaro
Journal of Clinical Medicine. 2021; 10(13): 2825
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151 Protective Effects Induced by a Hydroalcoholic Allium sativum Extract in Isolated Mouse Heart
Lucia Recinella, Annalisa Chiavaroli, Fabrizio Masciulli, Caterina Fraschetti, Antonello Filippi, Stefania Cesa, Francesco Cairone, Era Gorica, Marinella De Leo, Alessandra Braca, Alma Martelli, Vincenzo Calderone, Giustino Orlando, Claudio Ferrante, Luigi Menghini, Simonetta Cristina Di Simone, Serena Veschi, Alessandro Cama, Luigi Brunetti, Sheila Leone
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152 Efficacy of a Dietary Polyherbal Formula on the Performance and Gut Health in Broiler Chicks after Experimental Infection with Eimeria spp.
Vasilios Tsiouris, Ilias Giannenas, Eleftherios Bonos, Elias Papadopoulos, Ioanna Stylianaki, Erasmia Sidiropoulou, Diamanto Lazari, Athina Tzora, Bhaskar Ganguly, Ioanna Georgopoulou
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153 3D Bioprinted Bacteriostatic Hyperelastic Bone Scaffold for Damage-Specific Bone Regeneration
Mohammadreza Shokouhimehr, Andrea S. Theus, Archana Kamalakar, Liqun Ning, Cong Cao, Martin L. Tomov, Jarred M. Kaiser, Steven Goudy, Nick J. Willett, Ho Won Jang, Christopher N. LaRock, Philip Hanna, Aron Lechtig, Mohamed Yousef, Janaina Da Silva Martins, Ara Nazarian, Mitchel B. Harris, Morteza Mahmoudi, Vahid Serpooshan
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154 Improved Activity against Acute Myeloid Leukemia with Chimeric Antigen Receptor (CAR)-NK-92 Cells Designed to Target CD123
Michael A. Morgan, Arnold Kloos, Daniela Lenz, Nadine Kattre, Juliette Nowak, Marco Bentele, Maximilian Keisker, Julia Dahlke, Katharina Zimmermann, Martin Sauer, Michael Heuser, Axel Schambach
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155 Narrowing down the number of potential plant-based probiotic candidates by successive in vitro, technological and in vivo assays
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156 Melatonin and Vitamin C modulate cassava diet-induced alteration in reproductive and thyroid functions
OloruntobiOluwasegun Maliki, AbdullateefIsiaka Alagbonsi, ComfortMoyinoluwa Ibitoye, LuqmanAribidesi Olayaki
Nigerian Journal of Experimental and Clinical Biosciences. 2021; 9(3): 133
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157 Exercise Training Attenuates Ovariectomy-Induced Alterations in Skeletal Muscle Remodeling, Apoptotic Signaling, and Atrophy Signaling in Rat Skeletal Muscle
Eun-Jeong Cho, Youngju Choi, Jiyeon Kim, Jun Hyun Bae, Jinkyung Cho, Dong-Ho Park, Ju-Hee Kang, Jin Hwan Yoon, Eunmi Park, Dae Yun Seo, Sukho Lee, Hyo-Bum Kwak
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158 Cancer immunotherapy by NC410, a LAIR-2 Fc protein blocking human LAIR-collagen interaction
M Ines Pascoal Ramos, Linjie Tian, Emma J de Ruiter, Chang Song, Ana Paucarmayta, Akashdip Singh, Eline Elshof, Saskia V Vijver, Jahangheer Shaik, Jason Bosiacki, Zachary Cusumano, Christina Jensen, Nicholas Willumsen, Morten A Karsdal, Linda Liu, Sol Langermann, Stefan Willems, Dallas Flies, Linde Meyaard
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159 The effects of dexmedetomidine against ruptured abdominal aortic aneurysm injury to myocardial tissue induced by abdominal aorta clamping
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160 3,6’-dithiopomalidomide reduces neural loss, inflammation, behavioral deficits in brain injury and microglial activation
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161 The effect difference of chitosan nanoparticles, chitosan microparticles, and casein phosphopeptide–amorphous calcium phosphate in reducing enamel demineralization
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162 Evaluation of Topical Anti-Inflammatory Effects of a Gel Formulation with Plantago Lanceolata, Achillea Millefolium, Aesculus Hippocastanum and Taxodium Distichum
Anca Zanfirescu, Georgiana Nitulescu, Gheorghe Stancov, Denise Radulescu, Cosmin Trif, George Mihai Nitulescu, Simona Negres, Octavian Tudorel Olaru
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163 Attenuation of Anxiety-Like Behavior by Helichrysum stoechas (L.) Moench Methanolic Extract through Up-Regulation of ERK Signaling Pathways in Noradrenergic Neurons
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164 Omega-3 Fatty Acid-Type Docosahexaenoic Acid Protects against Aß-Mediated Mitochondrial Deficits and Pathomechanisms in Alzheimer’s Disease-Related Animal Model
Yong Ho Park, Soo Jung Shin, Hyeon soo Kim, Sang Bum Hong, Sujin Kim, Yunkwon Nam, Jwa-Jin Kim, Kyu Lim, Jong-Seok Kim, Jin-il Kim, Seong Gak Jeon, Minho Moon
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165 Novel Therapeutic Approach for the Management of Mood Disorders: In Vivo and In Vitro Effect of a Combination of L-Theanine, Melissa officinalis L. and Magnolia officinalis Rehder & E.H. Wilson
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166 In Vivo Biological Evaluation of Orthodontically Moved Incisors after Replantation
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167 Nanostructured Carbonated Hydroxyapatite Associated to rhBMP-2 Improves Bone Repair in Rat Calvaria
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168 Evaluation of New Octacalcium Phosphate-Coated Xenograft in Rats Calvarial Defect Model on Bone Regeneration
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170 Anterior Commissure Regulates Neuronal Activity of Amygdalae and Influences Locomotor Activity, Social Interaction and Fear Memory in Mice
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171 Estimation of between-Cow Variability in Nutrient Digestion of Lactating Dairy Cows Fed Corn-Based Diets
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172 Multidirectional Pharma-Toxicological Study on Harpagophytum procumbens DC. ex Meisn.: An IBD-Focused Investigation
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173 Cetuximab-Mediated Protection from Hypoxia- Induced Cell Death: Implications for Therapy Sequence in Colorectal Cancer
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174 Increased Anxiety-Like Behavior in the Acute Phase of a Preclinical Model of Periodontal Disease
Bruna Luiza Roim Varotto, Raquel Chacon Ruiz Martinez, Flavia Venetucci Gouveia, Geiza Fernanda Antunes, Gisele Maria de Campos Fabri, Gerson Ballester, Reynaldo Antequera, Silvia Regina Dowgan Tesseroli de Siqueira, Erich Talamoni Fonoff, Manoel Jacobsen Teixeira, José Tadeu Tesseroli de Siqueira
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175 Development of novel pH-sensitive nanoparticle-based transdermal patch for management of rheumatoid arthritis
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176 Effect of pharmacological agents on relapse following orthodontic tooth movement:
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177 Mucosal Heterologous Prime/Boost Vaccination Induces Polyfunctional Systemic Immunity, Improving Protection Against Trypanosoma cruzi
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178 Cruzipain and Its Physiological Inhibitor, Chagasin, as a DNA-Based Therapeutic Vaccine Against Trypanosoma cruzi
Natacha Cerny, Augusto Ernesto Bivona, Andrés Sanchez Alberti, Sebastián Nicolás Trinitario, Celina Morales, Alejandro Cardoso Landaburu, Silvia Inés Cazorla, Emilio Luis Malchiodi
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The Influence of Nanostructured Hydroxyapatite Surface in the Early Stages of Osseointegration: A Multiparameter Animal Study in Low-Density Bone

Suelen Cristina Sartoretto, Jose Calasans-Maia, Rodrigo Resende, Eduardo Câmara, Bruna Ghiraldini, Fabio Jose Barbosa Bezerra, Jose Mauro Granjeiro, Monica Diuana Calasans-Maia
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Anti-Nociceptive and Anti-Inflammatory Activity of Hygrophila schulli Leaves

Gebretsadkan Hintsa Tekulu, Abrha Desta, Mebrahtom Gebrelibanos Hiben, Ephrem Mebrahtu Araya
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182 In vitro and in vivo anti-diabetic activity of Citrullus colocynthis pulpy flesh with seeds hydro-ethanolic extract
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183 Calcitonin receptor is required for T-antigen-induced prostate carcinogenesis
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185 The Effect of Vitamin D Administration on Leptin, Adiponectin and mRNA MCP-1 Levels in Adipose Tissue of Obese Female Wistar Rats
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186 Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0
Nathalie Percie du Sert, Amrita Ahluwalia, Sabina Alam, Marc T. Avey, Monya Baker, William J. Browne, Alejandra Clark, Innes C. Cuthill, Ulrich Dirnagl, Michael Emerson, Paul Garner, Stephen T. Holgate, David W. Howells, Viki Hurst, Natasha A. Karp, Stanley E. Lazic, Katie Lidster, Catriona J. MacCallum, Malcolm Macleod, Esther J. Pearl, Ole H. Petersen, Frances Rawle, Penny Reynolds, Kieron Rooney, Emily S. Sena, Shai D. Silberberg, Thomas Steckler, Hanno Würbel, Isabelle Boutron
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188 Restoration of Cyclo-Gly-Pro-induced salivary hyposecretion and submandibular composition by naloxone in mice
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201 In vitro and in vivo anti-inflammatory properties of Mayan propolis
Jorge Xool-Tamayo, Ivan Chan-Zapata, Víctor Ermilo Arana-Argaez, Fabiola Villa-de la Torre, Julio César Torres-Romero, Jesus Alfredo Araujo-Leon, Fernando J Aguilar-Ayala, Marina E Rejón-Peraza, Nelly C Castro-Linares, Rossana F Vargas-Coronado, Juan V Cauich-Rodríguez
European Journal of Inflammation. 2020; 18: 2058739220
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202 Protective effects of ischemic preconditioning against neuronal apoptosis and dendritic injury in the hippocampus are age-dependent
Tsong-Hai Lee, Jen-Tsung Yang, Jr-Rung Lin, Chaur-Jong Hu, Wen-Hai Chou, Ching-Po Lin, Nai-Fang Chi
Journal of Neurochemistry. 2020; 155(4): 430
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203 Acute Effects of Two Different Species of Amyloid-ß on Oscillatory Activity and Synaptic Plasticity in the Commissural CA3-CA1 Circuit of the Hippocampus
Cécile Gauthier-Umaña, Jonathan Muñoz-Cabrera, Mario Valderrama, Alejandro Múnera, Mauricio O. Nava-Mesa, Javier M rquez Ruiz
Neural Plasticity. 2020; 2020: 1
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204 Sorafenib and Mesenchymal Stem Cell Therapy: A Promising Approach for Treatment of HCC
Saieh Hajighasemlou, Mohsen Nikbakht, Saeedreza Pakzad, Samad Muhammadnejad, Safoora Gharibzadeh, Milad Mirmoghtadaei, Fariba Zafari, Iman Seyhoun, Jafar Ai, Javad Verdi
Evidence-Based Complementary and Alternative Medicine. 2020; 2020: 1
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205 Phenylalanine induces pulmonary hypertension through calcium-sensing receptor activation
Rubin Tan, Jiansha Li, Fangbo Liu, Pu Liao, Matthieu Ruiz, Jocelyn Dupuis, Liping Zhu, Qinghua Hu
American Journal of Physiology-Lung Cellular and Molecular Physiology. 2020; 319(6): L1010
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206 Transplanted senescent renal scattered tubular-like cells induce injury in the mouse kidney
Seo Rin Kim, Kai Jiang, Christopher M. Ferguson, Hui Tang, Xiaojun Chen, XiangYang Zhu, LaTonya J. Hickson, Tamara Tchkonia, James L. Kirkland, Lilach O. Lerman
American Journal of Physiology-Renal Physiology. 2020; 318(5): F1167
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207 YAP confers resistance to vandetanib in medullary thyroid cancer
Huan Wang, Jian Tang, Zhiwei Su
Biochemistry and Cell Biology. 2020; 98(3): 443
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208 Analgesia additive interaction between tadalafil and morphine in an experimental animal model
Mohammed Mehanna, Souraya Domiati, Hania Nakkash Chmaisse, Ahmed El Mallah
Canadian Journal of Physiology and Pharmacology. 2020; 98(11): 771
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209 Prolonged Analgesia by Spinal Cord Stimulation Following a Spinal Injury Associated With Activation of Adult Neural Progenitors
Liting Sun, Sue Fleetwood-Walker, Rory Mitchell, Elbert A. Joosten, Chi Wai Cheung
Pain Practice. 2020; 20(8): 859
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210 Gene dosage manipulation alleviates manifestations of hereditary PAX6 haploinsufficiency in mice
Behnam Rabiee, Khandaker N. Anwar, Xiang Shen, Ilham Putra, Mingna Liu, Rebecca Jung, Neda Afsharkhamseh, Mark I. Rosenblatt, Gerald A. Fishman, Xiaorong Liu, Mahmood Ghassemi, Ali R. Djalilian
Science Translational Medicine. 2020; 12(573)
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211 An evaluation of the anti-hyperalgesic effects of cannabidiolic acid-methyl ester in a preclinical model of peripheral neuropathic pain
Yong Fang Zhu, Katja Linher-Melville, Mohammad Javad Niazmand, Manu Sharma, Ayesha Shahid, Kan Lun Zhu, Natalka Parzei, Jesse Sidhu, Christeene Haj, Raphael Mechoulam, Gurmit Singh
British Journal of Pharmacology. 2020; 177(12): 2712
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212 The effect of maslinic acid on cognitive dysfunction induced by cholinergic blockade in mice
Ho Jung Bae, Jihyun Kim, Jaehoon Kim, Nayeon Goo, Mudan Cai, Kyungnam Cho, Seo Yun Jung, Huiyoung Kwon, Dong Hyun Kim, Dae Sik Jang, Jong Hoon Ryu
British Journal of Pharmacology. 2020; 177(14): 3197
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213 Hesperidin attenuates altered redox homeostasis in an experimental hyperlipidaemic model of rat
Raushan Kumar, Farhan Akhtar, Syed Ibrahim Rizvi
Clinical and Experimental Pharmacology and Physiology. 2020; 47(4): 571
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214 Pregabalin administration and withdrawal affect testicular structure and functions in rats
Mohammad Salem Hareedy, Khaled Mohamed Tawfik, Dalia M. Badary, Waleed Ahmed Mahmoud, Essam_Elden Mohamed Mohamed
Andrologia. 2020; 52(11)
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215 Perioperative Neurocognitive Disorder
Roderic G. Eckenhoff, Mervyn Maze, Zhongcong Xie, Deborah J. Culley, Sarah J. Goodlin, Zhiyi Zuo, Huafeng Wei, Robert A. Whittington, Niccolò Terrando, Beverley A. Orser, Maryellen F. Eckenhoff
Anesthesiology. 2020; 132(1): 55
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216 Competitive Interactions between Halothane and Isoflurane at the Carotid Body and TASK Channels
Jaideep J. Pandit, Nicky Huskens, Peadar B. O’Donohoe, Philip J. Turner, Keith J. Buckler
Anesthesiology. 2020; 133(5): 1046
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217 Mitochondrial UQCRC1 mutations cause autosomal dominant parkinsonism with polyneuropathy
Chin-Hsien Lin, Pei-I Tsai, Han-Yi Lin, Nobutaka Hattori, Manabu Funayama, Beomseok Jeon, Kota Sato, Koji Abe, Yohei Mukai, Yuji Takahashi, Yuanzhe Li, Kenya Nishioka, Hiroyo Yoshino, Kensuke Daida, Meng-Ling Chen, Jay Cheng, Cheng-Yen Huang, Shiou-Ru Tzeng, Yen-Sheng Wu, Hsing-Jung Lai, Hsin-Hsi Tsai, Ruoh-Fang Yen, Ni-Chung Lee, Wen-Chun Lo, Yu-Chien Hung, Chih-Chiang Chan, Yi-Ci Ke, Chi-Chao Chao, Sung-Tsang Hsieh, Matthew Farrer, Ruey-Meei Wu
Brain. 2020; 143(11): 3352
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218 Premobilization of CD133+ progenitors is associated with attenuated inflammation-induced pulmonary dysfunction following extracorporeal circulation in mice
Dan Luo, Xinhao Liu, Jie Zhang, Lei Du, Lin Bai, Shuhua Luo
Interactive CardioVascular and Thoracic Surgery. 2020; 31(2): 210
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219 Cannabinoid receptors are differentially regulated in the pancreatic islets during the early development of metabolic syndrome
Antonio Barajas-Martínez, Karina Bermeo, Lizbeth de la Cruz, Marina Martínez-Vargas, Ricardo Jesús Martínez-Tapia, David Erasmo García, Luz Navarro
Islets. 2020; 12(6): 134
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220 Maternal soy protein isolate diet during lactation programmes to higher metabolic risk in adult male offspring
Poliana Guiomar de Almeida Brasiel, Maíra Schuchter Ferreira, Adriana Moura Vieira, Mariana Sarto Figueiredo, Patrícia Cristina Lisboa, Egberto Gaspar de Moura, Fernando Cesar Ferraz Lopes, Aline Silva de Aguiar, Sheila Cristina Potente Luquetti Dutra
International Journal of Food Sciences and Nutrition. 2020; 71(8): 954
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221 Interrogation of kinase genetic interactions provides a global view of PAK1-mediated signal transduction pathways
Jae-Hong Kim, Yeojin Seo, Myungjin Jo, Hyejin Jeon, Young-Seop Kim, Eun-Jung Kim, Donggun Seo, Won-Ha Lee, Sang Ryong Kim, Nozomu Yachie, Quan Zhong, Marc Vidal, Frederick P. Roth, Kyoungho Suk
Journal of Biological Chemistry. 2020; 295(50): 16906
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222 Neuroprotection by trans-resveratrol against collagenase-induced neurological and neurobehavioural deficits in rats involves adenosine A1 receptors
Noor Azliza Wani Abd. Aziz, Igor Iezhitsa, Renu Agarwal, Roqiah Fatmawati Abdul Kadir, Azian Abd. Latiff, Nafeeza Mohd Ismail
Neurological Research. 2020; 42(3): 189
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223 A High-Fructose Diet Formulated with Thermally Oxidized Monounsaturated Fat Aggravates Metabolic Dysregulation in Colon Epithelial Tissues of Rats
Arunaksharan Narayanankutty, Balu T. Kuzhivelil, Achuthan C. Raghavamenon
Journal of the American College of Nutrition. 2020; : 1
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224 Antinflammatory, antioxidant, and behavioral effects induced by administration of growth hormone-releasing hormone analogs in mice
Lucia Recinella, Annalisa Chiavaroli, Giustino Orlando, Claudio Ferrante, Guya Diletta Marconi, Iacopo Gesmundo, Riccarda Granata, Renzhi Cai, Wei Sha, Andrew V. Schally, Luigi Brunetti, Sheila Leone
Scientific Reports. 2020; 10(1)
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225 Preserving Airway Smooth Muscle Contraction in Precision-Cut Lung Slices
Guang Li, Jonathan A. Cohen, Carolina Martines, Sumati Ram-Mohan, Joseph D. Brain, Ramaswamy Krishnan, Xingbin Ai, Yan Bai
Scientific Reports. 2020; 10(1)
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226 Cannabinoids affect the mouse visual acuity via the cannabinoid receptor type 2
Bruno Cécyre, Ismaël Bachand, François Papineau, Chloé Brochu, Christian Casanova, Jean-François Bouchard
Scientific Reports. 2020; 10(1)
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227 Similar cognitive deficits in mice and humans in the chronic phase post-stroke identified using the touchscreen-based paired-associate learning task
Wei Zhen Chow, Lin Kooi Ong, Murielle G. Kluge, Prajwal Gyawali, Frederick R. Walker, Michael Nilsson
Scientific Reports. 2020; 10(1)
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228 CD30 and ALK combination therapy has high therapeutic potency in RANBP2-ALK-rearranged epithelioid inflammatory myofibroblastic sarcoma
Ashleigh M. Fordham, Jinhan Xie, Andrew J. Gifford, Carol Wadham, Lisa T. Morgan, Emily V. A. Mould, Mitali Fadia, Lei Zhai, Hassina Massudi, Zara S. Ali, Glenn M. Marshall, Robyn E. Lukeis, Jamie I. Fletcher, Karen L. MacKenzie, Toby N. Trahair
British Journal of Cancer. 2020; 123(7): 1101
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229 Hotspot mutant p53-R273H inhibits KLF6 expression to promote cell migration and tumor metastasis
Shengnan Sun, Hu Chen, Lijuan Sun, Miao Wang, Xianqiang Wu, Zhi-Xiong Jim Xiao
Cell Death & Disease. 2020; 11(7)
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230 Identification of therapeutics that target eEF1A2 and upregulate utrophin A translation in dystrophic muscles
Christine Péladeau, Nadine Adam, Lucas M. Bronicki, Adèle Coriati, Mohamed Thabet, Hasanen Al-Rewashdy, Jason Vanstone, Alan Mears, Jean-Marc Renaud, Martin Holcik, Bernard J. Jasmin
Nature Communications. 2020; 11(1)
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231 Retinal innervation tunes circuits that drive nonphotic entrainment to food
Diego Carlos Fernandez, Ruchi Komal, Jennifer Langel, Jun Ma, Phan Q. Duy, Mario A. Penzo, Haiqing Zhao, Samer Hattar
Nature. 2020; 581(7807): 194
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232 Vitamin A does not influence mRNA expression of hormone hepcidin but other biomarkers of iron homeostasis in young male Wistar rats
Mauricio Restrepo-Gallego, Luis E. Díaz
International Journal for Vitamin and Nutrition Research. 2020; : 1
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233 Genetic landscape and ligand-dependent activation of sonic hedgehog-Gli1 signaling in chordomas: a novel therapeutic target
Chenlong Yang, Lei Yong, Chen Liang, Yan Li, Yunlong Ma, Feng Wei, Liang Jiang, Hua Zhou, Guanping He, Xiaoyu Pan, Bao Hai, Jian Wu, Yulun Xu, Zhongjun Liu, Xiaoguang Liu
Oncogene. 2020; 39(24): 4711
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234 Crude extract of Camellia oleifera pomace ameliorates the progression of non-alcoholic fatty liver disease via decreasing fat accumulation, insulin resistance and inflammation
Wan-Ju Yeh, Jung Ko, Wen-Chih Huang, Wei-Yi Cheng, Hsin-Yi Yang
British Journal of Nutrition. 2020; 123(5): 508
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235 Severe below-maintenance feed intake increases methane yield from enteric fermentation in cattle
J. P. Goopy, D. Korir, D. Pelster, A. I. M. Ali, S. E. Wassie, E. Schlecht, U. Dickhoefer, L. Merbold, K. Butterbach-Bahl
British Journal of Nutrition. 2020; 123(11): 1239
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236 Hypericin-Loaded Transferrin Nanoparticles Induce PP2A-Regulated BMI1 Degradation in Colorectal Cancer-Specific Chemo-Photodynamic Therapy
Mohammed Nadim Sardoiwala, Avinash Chandra Kushwaha, Atul Dev, Nishith Shrimali, Prasenjit Guchhait, Surajit Karmakar, Subhasree Roy Choudhury
ACS Biomaterials Science & Engineering. 2020; 6(5): 3139
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237 LCZ696 (sacubitril/valsartan) protects against cyclophosphamide-induced testicular toxicity in rats: Role of neprilysin inhibition and lncRNA TUG1 in ameliorating apoptosis
Rania M. Salama, Azza H. Abd Elwahab, Mona M. Abd-Elgalil, Noura F. Elmongy, Mona F. Schaalan
Toxicology. 2020; 437: 152439
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238 Transcriptional Correlates of Tolerance and Lethality in Mice Predict Ebola Virus Disease Patient Outcomes
Adam Price, Atsushi Okumura, Elaine Haddock, Friederike Feldmann, Kimberly Meade-White, Pryanka Sharma, Methinee Artami, W. Ian Lipkin, David W. Threadgill, Heinz Feldmann, Angela L. Rasmussen
Cell Reports. 2020; 30(6): 1702
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239 Hexanucleotide Repeat Expansions in c9FTD/ALS and SCA36 Confer Selective Patterns of Neurodegeneration In Vivo
Tiffany W. Todd, Zachary T. McEachin, Jeannie Chew, Alexander R. Burch, Karen Jansen-West, Jimei Tong, Mei Yue, Yuping Song, Monica Castanedes-Casey, Aishe Kurti, Judith H. Dunmore, John D. Fryer, Yong-Jie Zhang, Beatriz San Millan, Susana Teijeira Bautista, Manuel Arias, Dennis Dickson, Tania F. Gendron, María-Jesús Sobrido, Matthew D. Disney, Gary J. Bassell, Wilfried Rossoll, Leonard Petrucelli
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240 Vcp Overexpression and Leucine Supplementation Increase Protein Synthesis and Improve Fear Memory and Social Interaction of Nf1 Mutant Mice
Yu-Tzu Shih, Tzyy-Nan Huang, Hsiao-Tang Hu, Tzu-Li Yen, Yi-Ping Hsueh
Cell Reports. 2020; 31(13): 107835
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241 Effect of statins on orthodontic tooth movement: A systematic review of animal and clinical studies
Karthik Kommuri, Fawad Javed, Zohaib Akram, Junad Khan
Archives of Oral Biology. 2020; 111: 104665
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242 GABA-cannabinoid interplays in the dorsal hippocampus and basolateral amygdala mediate morphine-induced amnesia
Khadijeh Alsadat Sharifi, Ameneh Rezayof, Sakineh Alijanpour, Mohammad-Reza Zarrindast
Brain Research Bulletin. 2020; 157: 61
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243 Synthesis, biological evaluation and docking studies of a novel class of sulfur-bridged diazabicyclo[3.3.1]nonanes
Gabriele Murineddu, Battistina Asproni, Paola Corona, Stefania Gessi, Stefania Merighi, Enrica Battistello, Chiara Sturaro, Girolamo Calò, Nicoletta Galeotti, Veronika Temml, Sonja Herdlinger, Daniela Schuster, Gerard A. Pinna
Bioorganic Chemistry. 2020; 102: 104072
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244 Biomimetic and estrogenic fibers promote tissue repair in mice and human skin via estrogen receptor ß
Seungkuk Ahn, Christophe O. Chantre, Herdeline Ann M. Ardoña, Grant M. Gonzalez, Patrick H. Campbell, Kevin Kit Parker
Biomaterials. 2020; 255: 120149
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245 Quercetin mitigates monosodium glutamate-induced excitotoxicity of the spinal cord motoneurons in aged rats via p38 MAPK inhibition
Alaa El-Din L. Firgany, Nahla Reda Sarhan
Acta Histochemica. 2020; 122(5): 151554
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246 Distribution of “molybdenum disulfide/cobalt ferrite” nanocomposite in animal model of breast cancer, following injection via differential infusion flow rates
Mohammadhossein Shahsavari Alavijeh, Adel Maghsoudpour, Morteza Khayat, Iman Rad, Shadie Hatamie
Journal of Pharmaceutical Investigation. 2020; 50(6): 583
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247 Hypoglycemic, hypolipidemic, and hepatoprotective effects of Polyscias fulva (Hiern) Harms ethanolic bark extract in streptozotocin-induced diabetic Wistar rats
Julius K. Koech, Anastasia N. Nandwa, Benson N. Macharia, Lucia K. Keter, Nicholas M. Mwikwabe, Vivian C. Tuei
International Journal of Diabetes in Developing Countries. 2020; 40(4): 570
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248 Transplantation of human dental pulp stem cells in streptozotocin-induced diabetic rats
Ahmed Othman Fathy Othman El-Kersh, Gehan El-Akabawy, Rasha H. Al-Serwi
Anatomical Science International. 2020; 95(4): 523
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249 Antagonism of peripheral opioid receptors by methylnaltrexone does not prevent morphine tolerance in rats
Kim Juhani Blomqvist, Katarzyna Anna Dudek, Hanna Viisanen, Kert Mätlik, Fredrik Harry Gustav Ahlström, Jouko Laitila, Eija Anneli Kalso, Pekka Veli Rauhala, Tuomas Olavi Lilius
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250 Comparison of incisional hernia models in rats: an experimental study
M. Sahin, M. Saydam, K. B. Yilmaz, D. Ozturk, P. Demir, A. T. Arikok, M. Akinci, M. T. Ozer
Hernia. 2020; 24(6): 1275
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251 The variation of the posterior variance and Bayesian sample size determination
Jörg Martin, Clemens Elster
Statistical Methods & Applications. 2020;
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252 Quality of Preovulatory (GV) Oocytes in Mice after Injection of eCG at Various Stages of the Estrous Cycle
Ya. A. Ryabukha, D. A. Petrova, O. V. Zatsepina
Bulletin of Experimental Biology and Medicine. 2020; 168(3): 385
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253 Early protein restriction increases intra-islet GLP-1 production and pancreatic ß-cell proliferation mediated by the ß-catenin pathway
Chaiane Aline da Rosa-Santos, Priscila da Costa Rodrigues, Luana Resende Silva, Vanessa Cristina Arantes, Marise Auxiliadora de Barros Reis, Edson Moleta Colodel, Amílcar Sabino Damazo, Egberto Gaspar de Moura, Everardo Magalhães Carneiro, Márcia Queiroz Latorraca
European Journal of Nutrition. 2020; 59(8): 3565
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254 Rational application of targeted therapeutics in mucinous colon/appendix cancers with positive predictive factors
Ashokkumar Dilly, Brendon D. Honick, Yong J. Lee, David L. Bartlett, Haroon A. Choudry
Cancer Medicine. 2020; 9(5): 1753
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255 Assessment of Problem-Solving Skills and Inhibitory Control in Mice Using Water Escape Detour Test
Grzegorz R. Juszczak, Anna Bobrowska
Current Protocols in Mouse Biology. 2020; 10(3)
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256 The impact of periodontitis in the course of chronic obstructive pulmonary disease: Pulmonary and systemic effects
Ellen Perim Rosa, Felipe Murakami-Malaquias-da-Silva, Marlon Palma-Cruz, Geovana de Carvalho Garcia, Auriléia Aparecida Brito, Lucas Andreo, Sergio Koiti Kamei, Renata Matalon Negreiros, Maria Fernanda De Souza Setubal Destro Rodrigues, Raquel Agnelli Mesquita-Ferrari, Sandra Kalil Bussadori, Kristianne Porta Santos Fernandes, Ana Paula Ligeiro-de-Oliveira, Adriana Lino-Dos-Santos-Franco, Anna Carolina Ratto Tempestini Horliana
Life Sciences. 2020; 261: 118257
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257 Mucosal characteristics vary across developmental stages in the small intestine of C57BL/6J mice
Christine J. Park, Matthew P. Shaughnessy, Robert A. Cowles
Life Sciences. 2020; 260: 118428
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258 Neuroprotective effects of vildagliptin on drug induced Alzheimer's disease in rats with metabolic syndrome: Role of hippocampal klotho and AKT signaling pathways
Rasha R. Yossef, Mohamed F. Al-Yamany, Muhammed A. Saad, Ayman E. El-Sahar
European Journal of Pharmacology. 2020; 889: 173612
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259 Pomegranate-derived anthocyanin regulates MORs-cAMP/CREB-BDNF pathways in opioid-dependent models and improves cognitive impairments
Norhaslinda Ridzwan, Mimie Noratiqah Jumli, Atif Amin Baig, Mohd Adzim Khalili Rohin
Journal of Ayurveda and Integrative Medicine. 2020; 11(4): 478
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260 The ameliorative effects of a phenolic derivative of Moringa oleifera leave against vanadium-induced neurotoxicity in mice
Olumayowa O. Igado, Anna Andrioli, Idris A. Azeez, Francesco Girolamo, Mariella Errede, Oluwasanmi O. Aina, Jan Glaser, Ulrike Holzgrabe, Marina Bentivoglio, James O. Olopade
IBRO Reports. 2020; 9: 164
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261 l-lysine confers neuroprotection by suppressing inflammatory response via microRNA-575/PTEN signaling after mouse intracerebral hemorrhage injury
Jing Cheng, Jun-Chun Tang, Meng-Xian Pan, Song-Feng Chen, Dan Zhao, Ya Zhang, Hua-Bao Liao, Yang Zhuang, Rui-Xue Lei, Shu Wang, An-Chun Liu, Juan Chen, Zhao-Hui Zhang, Huan-Ting Li, Qi Wan, Qian-Xue Chen
Experimental Neurology. 2020; 327: 113214
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262 Epistatic evidence for gender-dependant slow neurotransmission signalling in substance use disorders: PPP1R12B versus PPP1R1B
Kefu Liu, Juan Zhao, Chunnuan Chen, Jie Xu, Richard L. Bell, Frank S. Hall, George F. Koob, Nora D. Volkow, Hong Qing, Zhicheng Lin
EBioMedicine. 2020; 61: 103066
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263 Thoracic sympathetic nuclei ischemia: Effects on lower heart rates following experimentally induced spinal subarachnoid hemorrhage
Y. Koza, E. Bayram, E. Armagan Koza, M.D. Aydin, C. Soyalp, C. Atalay, S. Sipal
Neurochirurgie. 2020; 66(3): 155
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264 Protein restriction during pregnancy impairs intra-islet GLP-1 and the expansion of ß-cell mass
Edson Henrique Pereira de Arruda, Gleicielly Leite Vieira da Silva, Chaiane Aline da Rosa-Santos, Vanessa Cristina Arantes, Marise Auxiliadora de Barros Reis, Edson Moleta Colodel, Egberto Gaspar de Moura, Patrícia Cristina Lisboa, Everardo Magalhães Carneiro, Amílcar Sabino Damazo, Márcia Queiroz Latorraca
Molecular and Cellular Endocrinology. 2020; 518: 110977
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265 Counter-regulatory responses to Telfairia occidentalis-induced hypoglycaemia
Toyin Mohammed Salman, Isiaka Abdullateef Alagbonsi, Sheu Oluwadare Sulaiman
Metabolism Open. 2020; 8: 100065
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266 Apoptotic blebs from Leishmania major-infected macrophages as a new approach for cutaneous leishmaniasis vaccination
Roghiyeh Faridnia, Hamed Kalani, Hajar Ziaei Hezarjaribi, Paul W. Denny, Alireza Rafie, Mahdi Fakhar, Stela Virgilio
Microbial Pathogenesis. 2020; 147: 104406
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267 Examining the role of muscarinic M5 receptors in VTA cholinergic modulation of depressive-like and anxiety-related behaviors in rats
Eric J. Nunes, Laura E. Rupprecht, Daniel J. Foster, Craig W. Lindsley, P. Jeffrey Conn, Nii A. Addy
Neuropharmacology. 2020; 171: 108089
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268 Topical photodynamic therapy of tumor bearing mice with meso-tetrakis (N-methyl-4-pyridyl) porphyrin loaded in ethosomes
Maha Fadel, Kawser Kassab, Doaa A. Abdel Fadeel, Maha A. Farag
Photodiagnosis and Photodynamic Therapy. 2020; 30: 101789
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269 Saliva renal function biomarkers as alternatives to plasma concentrations in obesity-induced kidney injury
Christian Eseigbe Imafidon, Rufus Ojo Akomolafe, Oluwamayowa Gracious Oke
Obesity Medicine. 2020; 17: 100195
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270 Zingiber officinale Roscoe rhizome extract alleviates neuropathic pain by inhibiting neuroinflammation in mice
Vittoria Borgonetti, Paolo Governa, Marco Biagi, Federica Pellati, Nicoletta Galeotti
Phytomedicine. 2020; 78: 153307
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271 Targeting the vascular endothelial growth factor receptor-1 by the monoclonal antibody D16F7 to increase the activity of immune checkpoint inhibitors against cutaneous melanoma
Pedro Miguel Lacal, Maria Grazia Atzori, Federica Ruffini, Manuel Scimeca, Elena Bonanno, Rosella Cicconi, Maurizio Mattei, Roberta Bernardini, Stefania D’Atri, Lucio Tentori, Grazia Graziani
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272 Safety evaluation and antihyperglycaemic effect of root extract of Maerua decumbens (Brongn.) DeWolf in Wistar rats
Richard T. Kiptisia, Geoffrey K. Maiyoh, Benson N. Macharia, Vivian C. Tuei
Scientific African. 2020; 8: e00379
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273 Surgical or non-surgical treatment of peri-implantitis — what is the verdict?,
Elli Anna Kotsailidi, Dimitrios Michelogiannakis, Abeer Sami Al-Zawawi, Fawad Javed
Surgery in Practice and Science. 2020; 1: 100010
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274 Enhanced CAR–T cell activity against solid tumors by vaccine boosting through the chimeric receptor
Leyuan Ma, Tanmay Dichwalkar, Jason Y. H. Chang, Benjamin Cossette, Daniel Garafola, Angela Q. Zhang, Michael Fichter, Chensu Wang, Simon Liang, Murillo Silva, Sudha Kumari, Naveen K. Mehta, Wuhbet Abraham, Nikki Thai, Na Li, K. Dane Wittrup, Darrell J. Irvine
Science. 2019; 365(6449): 162
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275 Experimental Designs and Number of Animal to Increase Efficiency in Animal Experiments
Anadolu Klinigi Tip Bilimleri Dergisi. 2019; 24(3): 248
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276 Adding a C-terminal Cysteine (CTC) Can Enhance the Bactericidal Activity of Three Different Antimicrobial Peptides
Heng-Li Chen,Pei-Yi Su,Shu-Chen Kuo,Tsai-Ling Y. Lauderdale,Chiaho Shih
Frontiers in Microbiology. 2018; 9
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277 Apolipoprotein E-Mimetic Peptide COG1410 Promotes Autophagy by Phosphorylating GSK-3ß in Early Brain Injury Following Experimental Subarachnoid Hemorrhage
Xinshen Li,Jianhua Peng,Jinwei Pang,Yue Wu,Xueping Huang,Yong Li,Jian Zhou,Long Gu,Xiaochuan Sun,Ligang Chen,Michael P. Vitek,Yong Jiang
Frontiers in Neuroscience. 2018; 12
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278 Lead-Induced Atypical Parkinsonism in Rats: Behavioral, Electrophysiological, and Neurochemical Evidence for a Role of Noradrenaline Depletion
Mariam Sabbar,Claire Delaville,Philippe De Deurwaerdère,Nouria Lakhdar-Ghazal,Abdelhamid Benazzouz
Frontiers in Neuroscience. 2018; 12
[Pubmed] | [DOI]
279 Social Company Disrupts Fear Memory Renewal: Evidence From Two Rodent Studies
Jiajin Yuan,Minmin Yan,Yin Xu,Weihai Chen,Xiaqing Wang
Frontiers in Neuroscience. 2018; 12
[Pubmed] | [DOI]
280 The motivation-based calving facility: Social and cognitive factors influence isolation seeking behaviour of Holstein dairy cows at calving
Maria Vilain Rørvang,Mette S. Herskin,Margit Bak Jensen,Juan J. Loor
PLOS ONE. 2018; 13(1): e0191128
[Pubmed] | [DOI]
281 Reconstruction of a 10-mm-long median nerve gap in an ischemic environment using autologous conduits with different patterns of blood supply: A comparative study in the rat
Diogo Casal,Eduarda Mota-Silva,Inês Iria,Sara Alves,Ana Farinho,Cláudia Pen,Nuno Lourenço-Silva,Luís Mascarenhas-Lemos,José Silva-Ferreira,Mário Ferraz-Oliveira,Valentina Vassilenko,Paula Alexandra Videira,João Goyri-O’Neill,Diogo Pais,William D. Phillips
PLOS ONE. 2018; 13(4): e0195692
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282 Natural disease history of the dy2J mouse model of laminin a2 (merosin)-deficient congenital muscular dystrophy
S. Pasteuning-Vuhman,K. Putker,C. L. Tanganyika-de Winter,J. W. Boertje-van der Meulen,L. van Vliet,M. Overzier,J. J. Plomp,A. Aartsma-Rus,M. van Putten,Atsushi Asakura
PLOS ONE. 2018; 13(5): e0197388
[Pubmed] | [DOI]
283 Trypanosoma cruzi 80 kDa prolyl oligopeptidase (Tc80) as a novel immunogen for Chagas disease vaccine
Augusto E. Bivona,Andrés Sánchez Alberti,Marina N. Matos,Natacha Cerny,Alejandro C. Cardoso,Celina Morales,Germán González,Silvia I. Cazorla,Emilio L. Malchiodi,Walderez O. Dutra
PLOS Neglected Tropical Diseases. 2018; 12(3): e0006384
[Pubmed] | [DOI]
284 Co-occurrence of opisthorchiasis and diabetes exacerbates morbidity of the hepatobiliary tract disease
Apisit Chaidee,Sudarat Onsurathum,Kitti Intuyod,Patchareewan Pannangpetch,Chatlert Pongchaiyakul,Porntip Pinlaor,Chawalit Pairojkul,Wannaporn Ittiprasert,Christina J. Cochran,Victoria H. Mann,Paul J. Brindley,Somchai Pinlaor,Malcolm Jones
PLOS Neglected Tropical Diseases. 2018; 12(6): e0006611
[Pubmed] | [DOI]
285 Bovine Herpesvirus-4-Based Vector Delivering Peste des Petits Ruminants Virus Hemagglutinin ORF Induces both Neutralizing Antibodies and Cytotoxic T Cell Responses
Francesca Macchi,José Manuel Rojas,Andrea Elizabeth Verna,Noemí Sevilla,Valentina Franceschi,Giulia Tebaldi,Sandro Cavirani,Verónica Martín,Gaetano Donofrio
Frontiers in Immunology. 2018; 9
[Pubmed] | [DOI]
286 Disruption of Central Antioxidant Property of Nuclear Factor Erythroid 2-Related Factor 2 Worsens Circulatory Homeostasis with Baroreflex Dysfunction in Heart Failure
Takuya Kishi
International Journal of Molecular Sciences. 2018; 19(3): 646
[Pubmed] | [DOI]
287 Graminex Pollen: Phenolic Pattern, Colorimetric Analysis and Protective Effects in Immortalized Prostate Cells (PC3) and Rat Prostate Challenged with LPS
Marcello Locatelli,Nicola Macchione,Claudio Ferrante,Annalisa Chiavaroli,Lucia Recinella,Simone Carradori,Gokhan Zengin,Stefania Cesa,Lidia Leporini,Sheila Leone,Luigi Brunetti,Luigi Menghini,Giustino Orlando
Molecules. 2018; 23(5): 1145
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288 Recommendations for In Vitro and In Vivo Testing of Magnetic Nanoparticle Hyperthermia Combined with Radiation Therapy
Spiridon Spirou,Sofia Costa Lima,Penelope Bouziotis,Sanja Vranješ-Djuric,Eleni Efthimiadou,Anna Laurenzana,Ana Barbosa,Ignacio Garcia-Alonso,Carlton Jones,Drina Jankovic,Oliviero Gobbo
Nanomaterials. 2018; 8(5): 306
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289 Adjunctive buccal and palatal corticotomy for adult maxillary expansion in an animal model
My Huy Thuc Le,Seng Fong Lau,Norliza Ibrahim,Abu Kasim Noor Hayaty,Zamri Bin Radzi
The Korean Journal of Orthodontics. 2018; 48(2): 98
[Pubmed] | [DOI]
290 Understanding Echinocandin Resistance in the Emerging Pathogen Candida auris
Milena Kordalewska,Annie Lee,Steven Park,Indira Berrio,Anuradha Chowdhary,Yanan Zhao,David S. Perlin
Antimicrobial Agents and Chemotherapy. 2018; 62(6): e00238-18
[Pubmed] | [DOI]
291 G5G2.5 core-shell tecto-dendrimer specifically targets reactive glia in brain ischemia
Veronica Murta,Priscila Schilrreff,Gerardo Rosciszewski,Maria Jose Morilla,Alberto Javier Ramos
Journal of Neurochemistry. 2018;
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292 Absence of infiltrating peripheral myeloid cells in the brains of mouse models of lysosomal storage disorders
Soo Min Cho,Ayelet Vardi,Nicolas Platt,Anthony H. Futerman
Journal of Neurochemistry. 2018;
[Pubmed] | [DOI]
293 Inflammatory-induced spinal dorsal horn neurons hyperexcitability is mediated by P2X4 receptors
Franck Aby,Sara Whitestone,Marc Landry,Lauriane Ulmann,Pascal Fossat
PAIN Reports. 2018; 3(3): e660
[Pubmed] | [DOI]
294 Intraperitoneal, subcutaneous and intravenous glucagon delivery and subsequent glucose response in rats: a randomized controlled crossover trial
Ilze Dirnena-Fusini, Marte Kierulf Åm, Anders Lyngvi Fougner, Sven Magnus Carlsen, Sverre Christian Christiansen
BMJ Open Diabetes Research & Care. 2018; 6(1): e000560
[Pubmed] | [DOI]
295 Molecular Characterization of Newcastle Disease Virus from Backyard Poultry Farms and Live Bird Markets in Kenya
Irene N. Ogali,Lucy W. Wamuyu,Jacqueline K. Lichoti,Erick O. Mungube,Bernard Agwanda,Sheila C. Ommeh
International Journal of Microbiology. 2018; 2018: 1
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296 Inhibition of ID1–BMPR2 Intrinsic Signaling Sensitizes Glioma Stem Cells to Differentiation Therapy
Xiong Jin, Xun Jin, Leo J.Y. Kim, Deobrat Dixit, Hee-Young Jeon, Eun-Jung Kim, Jun-Kyum Kim, Seon Yong Lee, Jinlong Yin, Jeremy N. Rich, Hyunggee Kim
Clinical Cancer Research. 2018; 24(2): 383
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297 Anti-HER2 scFv-Directed Extracellular Vesicle-Mediated mRNA-Based Gene Delivery Inhibits Growth of HER2-Positive Human Breast Tumor Xenografts by Prodrug Activation
Jing-Hung Wang, Alexis V. Forterre, Jinjing Zhao, Daniel O. Frimannsson, Alain Delcayre, Travis J. Antes, Bradley Efron, Stefanie S. Jeffrey, Mark D. Pegram, A.C. Matin
Molecular Cancer Therapeutics. 2018; 17(5): 1133
[Pubmed] | [DOI]
298 Avocado soybean unsaponifiables ameliorates cartilage and subchondral bone degeneration in mono-iodoacetate-induced knee osteoarthritis in rats
Aliaa S.A. Al-Afify,Gehan El-Akabawy,Neveen M. El-Sherif,Fatma El-Nabawya A. El-Safty,Mostafa M. El-Habiby
Tissue and Cell. 2018; 52: 108
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299 Synthesis and Evaluation of Antiplasmodial Efficacy of ß-Carboline Derivatives against Murine Malaria
Varun Gorki, Rahul Singh, Neha Sylvia Walter, Upma Bagai, Deepak B. Salunke
ACS Omega. 2018; 3(10): 13200
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300 Hypocholesterolaemic effect of whole-grain highland hull-less barley in rats fed a high-fat diet
Xuejuan Xia,Guannan Li,Jiaxin Song,Jiong Zheng,Jianquan Kan
British Journal of Nutrition. 2018; 119(10): 1102
[Pubmed] | [DOI]
301 Cotransporter-mediated water transport underlying cerebrospinal fluid formation
Annette B. Steffensen,Eva K. Oernbo,Anca Stoica,Niklas J. Gerkau,Dagne Barbuskaite,Katerina Tritsaris,Christine R. Rose,Nanna MacAulay
Nature Communications. 2018; 9(1)
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302 A metabolic interplay coordinated by HLX regulates myeloid differentiation and AML through partly overlapping pathways
Indre Piragyte,Thomas Clapes,Aikaterini Polyzou,Ramon I. Klein Geltink,Stylianos Lefkopoulos,Na Yin,Pierre Cauchy,Jonathan D. Curtis,Lhéanna Klaeylé,Xavier Langa,Cora C. A. Beckmann,Marcin W. Wlodarski,Patrick Müller,Dominic Van Essen,Angelika Rambold,Friedrich G. Kapp,Marina Mione,Joerg M. Buescher,Erika L. Pearce,Alexander Polyzos,Eirini Trompouki
Nature Communications. 2018; 9(1)
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303 Targeting AURKA-CDC25C axis to induce synthetic lethality in ARID1A-deficient colorectal cancer cells
Changjie Wu,Junfang Lyu,Eun Ju Yang,Yifan Liu,Baoyuan Zhang,Joong Sup Shim
Nature Communications. 2018; 9(1)
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304 How much confidence do we need in animal experiments? Statistical assumptions in sample size estimation
Veronika Richter,Rainer Muche,Benjamin Mayer
Journal of Applied Animal Welfare Science. 2018; : 1
[Pubmed] | [DOI]
305 Effects of Resveratrol and Mangiferin on PPAR? and FALDH Gene Expressions in Adipose Tissue of Streptozotocin-Nicotinamide-Induced Diabetes in Rats
Purabi Sarkar,Ananya Bhowmick,Mohan Chandra Kalita,Sofia Banu
Journal of Dietary Supplements. 2018; : 1
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306 Fetal extracellular matrix nerve wraps locally improve peripheral nerve remodeling after complete transection and direct repair in rat
Tanchen Ren,Anne Faust,Yolandi van der Merwe,Bo Xiao,Scott Johnson,Apoorva Kandakatla,Vijay S. Gorantla,Stephen F. Badylak,Kia M. Washington,Michael B. Steketee
Scientific Reports. 2018; 8(1)
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307 Effects of central RVD-hemopressin(a) administration on anxiety, feeding behavior and hypothalamic neuromodulators in the rat
Lucia Recinella,Annalisa Chiavaroli,Claudio Ferrante,Adriano Mollica,Giorgia Macedonio,Azzurra Stefanucci,Marilisa Pia Dimmito,Szabolcs Dvorácskó,Csaba Tömböly,Luigi Brunetti,Giustino Orlando,Sheila Leone
Pharmacological Reports. 2018; 70(4): 650
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308 The benefits of soluble non-bacterial fraction of kefir on blood pressure and cardiac hypertrophy in hypertensive rats are mediated by an increase in baroreflex sensitivity and decrease in angiotensin-converting enzyme activity
Girlandia Alexandre Brasil,Mirian de Almeida Silva-Cutini,Flávia de Souza Andrade Moraes,Thiago de Melo Costa Pereira,Elisardo Corral Vasquez,Dominik Lenz,Nazaré Souza Bissoli,Denise Coutinho Endringer,Ewelyne Miranda de Lima,Vinícia Campana Biancardi,June Ferreira Maia,Tadeu Uggere de Andrade
Nutrition. 2018;
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309 Antidepressant-like actions by silencing of neuronal ELAV-like RNA-binding proteins HuB and HuC in a model of depression in male mice
Maria Domenica Sanna,Alessandro Quattrone,Nicoletta Galeotti
Neuropharmacology. 2018; 135: 444
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310 N-a-acetyltransferase 10 protein promotes metastasis by stabilizing matrix metalloproteinase-2 protein in human osteosarcomas
Ming-Hsien Chien,Wei-Jiunn Lee,Yi-Chieh Yang,Peng Tan,Ke-Fan Pan,Yu-Cheng Liu,Hsiao-Chi Tsai,Chun-Hua Hsu,Yu-Ching Wen,Michael Hsiao,Kuo-Tai Hua
Cancer Letters. 2018; 433: 86
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311 Crocus sativus L. stigmas and byproducts: Qualitative fingerprint, antioxidant potentials and enzyme inhibitory activities
Luigi Menghini,Lidia Leporini,Giulia Vecchiotti,Marcello Locatelli,Simone Carradori,Claudio Ferrante,Gokhan Zengin,Lucia Recinella,Annalisa Chiavaroli,Sheila Leone,Luigi Brunetti,Giustino Orlando
Food Research International. 2018; 109: 91
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312 Characterization of sleep-pattern and neuro-immune-endocrine markers at 24?hour post-injection of a single low dose of lipopolysaccharide in male Wistar rats
Francisco Nachón-García,Gabriela Hurtado-Alvarado,Mario E. Acosta-Hernández,Carolina Peña-Escudero,Sergio Priego-Fernández,Samantha Alvarez-Herrera,Enrique Becerril-Villanueva,Gilberto Pérez-Sánchez,Lenin Pavón,Fabio García-García
Journal of Neuroimmunology. 2018; 320: 15
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313 Mitochondrial uncoupling prodrug improves tissue sparing, cognitive outcome, and mitochondrial bioenergetics after traumatic brain injury in male mice
W. Brad Hubbard,Christopher L. Harwood,John G. Geisler,Hemendra J. Vekaria,Patrick G. Sullivan
Journal of Neuroscience Research. 2018;
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314 Lactobacillus rhamnosus intake can prevent the development of Candidiasis
Mariella Vieira Pereira Leão,Talita Angelina Aureliano Tavares,Célia Regina Gonçalves e Silva,Silvana Soleo Ferreira dos Santos,Juliana Campos Junqueira,Luciane Dias de Oliveira,Antonio Olavo Cardoso Jorge
Clinical Oral Investigations. 2018;
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315 Modulatory Effect of the Intracellular Content of Lactobacillus casei CRL 431 Against the Aflatoxin B1-Induced Oxidative Stress in Rats
J. E. Aguilar-Toalá,H. Astiazarán-García,M.C. Estrada-Montoya,H. S. Garcia,B. Vallejo-Cordoba,A. F. González-Córdova,A. Hernández-Mendoza
Probiotics and Antimicrobial Proteins. 2018;
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316 Immunohistochemical evaluation after Sr-enriched biphasic ceramic implantation in rabbits femoral neck: comparison of seven different bone conditions
Janis Zarins,Mara Pilmane,Elga Sidhoma,Ilze Salma,Janis Locs
Journal of Materials Science: Materials in Medicine. 2018; 29(8)
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317 Animal Pharmacokinetic/Pharmacodynamic Studies (APPS) Reporting Guidelines
Jasbir Singh,Fawzy Elbarbry,Ke Lan,Tomasz Grabowski
European Journal of Drug Metabolism and Pharmacokinetics. 2018;
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318 Predicting the sacculinid Sacculina beauforti infection status of the orange mud crab Scylla olivacea by discriminant analysis
Hanafiah Fazhan,Khor Waiho,Hin Boo Wee,Mohd Agos Surzanne,Hongyu Ma,Mhd Ikhwanuddin
Aquaculture. 2018; 491: 128
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319 Herb-drug interaction of Nisha Amalaki and Curcuminoids with metformin in normal and diabetic condition: A disease system approach
Sushant Shengule,Kalyani Kumbhare,Dada Patil,Sanjay Mishra,Kishori Apte,Bhushan Patwardhan
Biomedicine & Pharmacotherapy. 2018; 101: 591
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320 Polyphenolic composition, enzyme inhibitory effects ex-vivo and in-vivo studies on two Brassicaceae of north-central Italy
Adriano Mollica,Azzurra Stefanucci,Gokhan Zengin,Marcello Locatelli,Giorgia Macedonio,Giustino Orlando,Claudio Ferrante,Luigi Menghini,Lucia Recinella,Sheila Leone,Annalisa Chiavaroli,Lidia Leporini,Chiara Di Nisio,Luigi Brunetti,Eltayeb Tayrab,Islam Ali,Taha H. Musa,Hassan H. Musa,Abdelkareem A. Ahmed
Biomedicine & Pharmacotherapy. 2018; 107: 129
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321 Adiponectin regulates thermal nociception in a mouse model of neuropathic pain
L. Sun,H. Li,L.W. Tai,P. Gu,C.W. Cheung
British Journal of Anaesthesia. 2018;
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322 Importância do uso adequado da estatística básica nas pesquisas clínicas
Célio Fernando de Sousa Rodrigues,Fernando José Camello de Lima,Fabiano Timbó Barbosa
Brazilian Journal of Anesthesiology. 2017;
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323 Importance of using basic statistics adequately in clinical research
Célio Fernando de Sousa Rodrigues,Fernando José Camello de Lima,Fabiano Timbó Barbosa
Brazilian Journal of Anesthesiology (English Edition). 2017;
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324 Effect of amitriptyline treatment on neurofilament-H protein in an experimental model of depression
Maria Domenica Sanna,Carla Ghelardini,Nicoletta Galeotti
Brain Research Bulletin. 2017; 128: 1
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325 Low-intensity (400 mW/cm2, 500 kHz) pulsed transcranial ultrasound preconditioning may mitigate focal cerebral ischemia in rats
Hangdao Li,Junfeng Sun,Daqu Zhang,Daryl Omire-Mayor,Peter A. Lewin,Shanbao Tong
Brain Stimulation. 2017;
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326 A segmentation method for myocardial ischemia/infarction applicable in heart photos
Salety Ferreira Baracho,Daniel José Lins Leal Pinheiro,Carlos Marcelo Gurjão de Godoy,Regina Célia Coelho
Computers in Biology and Medicine. 2017; 87: 285
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327 Differential effects of total and partial sleep deprivation on salivary factors in Wistar rats
Dr. T.J. Lasisi,S.T. Shittu,C.C. Meludu,A.A. Salami
Archives of Oral Biology. 2017; 73: 100
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328 Intermittent hypoxia causes mandibular growth retardation and macroglossia in growing rats
Jun Hosomichi,Yo-ichiro Kuma,Shuji Oishi,Hisashi Nagai,Hideyuki Maeda,Risa Usumi-Fujita,Yasuhiro Shimizu,Sawa Kaneko,Chisa Shitano,Jun-ichi Suzuki,Ken-ichi Yoshida,Takashi Ono
American Journal of Orthodontics and Dentofacial Orthopedics. 2017; 151(2): 363
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329 Stability and efficacy of frozen and lyophilized fecal microbiota transplant (FMT) product in a mouse model of Clostridium difficile infection (CDI)
Zhi-Dong Jiang,Ashley Alexander,Shi Ke,Evangelia M. Valilis,Shaofan Hu,Bingjie Li,Herbert L. DuPont
Anaerobe. 2017; 48: 110
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330 Detrimental effect of maternal and post-weaning high-fat diet on the reproductive function in the adult female offspring rat: roles of insulin-like growth factor 2 and the ovarian circadian clock
Yu-Ju Lin,Ching-Chou Tsai,Li-Tung Huang,Jiunn-Ming Sheen,Mao-Meng Tiao,Hong-Ren Yu,Chih-Cheng Chen,You-Lin Tain
Journal of Assisted Reproduction and Genetics. 2017;
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331 New approach for the treatment of neuropathic pain: Fibroblast growth factor 1 gene-transfected adipose-derived mesenchymal stem cells
F. Forouzanfar,B. Amin,A. Ghorbani,H. Ghazavi,F. Ghasemi,K. Sadri,S. Mehri,H.R. Sadeghnia,H. Hosseinzadeh
European Journal of Pain. 2017;
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332 Optimization of Aqueous Extraction and Biological Activity of Harpagophytum procumbens Root on Ex Vivo Rat Colon Inflammatory Model
Marcello Locatelli,Claudio Ferrante,Simone Carradori,Daniela Secci,Lidia Leporini,Annalisa Chiavaroli,Sheila Leone,Lucia Recinella,Giustino Orlando,Sara Martinotti,Luigi Brunetti,Michele Vacca,Luigi Menghini
Phytotherapy Research. 2017;
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333 Protective Effects Induced by Microwave-Assisted Aqueous Harpagophytum Extract on Rat Cortex Synaptosomes Challenged with Amyloid ß-Peptide
Claudio Ferrante,Lucia Recinella,Marcello Locatelli,Paolo Guglielmi,Daniela Secci,Lidia Leporini,Annalisa Chiavaroli,Sheila Leone,Sara Martinotti,Luigi Brunetti,Michele Vacca,Luigi Menghini,Giustino Orlando
Phytotherapy Research. 2017;
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334 Resveratrol inhibits obesity-associated adipose tissue dysfunction and tumor growth in a mouse model of postmenopausal claudin-low breast cancer
Emily L. Rossi,Subreen A. Khatib,Steven S. Doerstling,Laura W. Bowers,Melissa Pruski,Nikki A. Ford,Randolph D. Glickman,Mengmeng Niu,Peiying Yang,Zhengrong Cui,John DiGiovanni,Stephen D. Hursting
Molecular Carcinogenesis. 2017;
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335 Assessment of corrected flow time in carotid artery via point-of-care ultrasonography: Reference values and the influential factors
Hooman Hossein-Nejad,Mohsen Banaie,Seyedhossein Seyedhosseini Davarani,Payam Mohammadinejad
Journal of Critical Care. 2017; 40: 46
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336 Effects of platelet-rich plasma against experimental ischemia/reperfusion injury in rat testis
C.A. Sekerci,Y. Tanidir,T.E. Sener,G. Sener,O. Cevik,A. Yarat,B. Alev-Tuzuner,S. Cetinel,E. Kervancioglu,A. Sahan,C. Akbal
Journal of Pediatric Urology. 2017;
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337 Granulocyte macrophage – colony stimulating factor (GM-CSF) significantly enhances articular cartilage repair potential by microfracture
M.-D. Truong,B.H. Choi,Y.J. Kim,M.S. Kim,B.-H. Min
Osteoarthritis and Cartilage. 2017;
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338 An approach towards accountability: suggestions for increased reproducibility in surgical destabilization of medial meniscus (DMM) models
A. Ratneswaran,F. Beier
Osteoarthritis and Cartilage. 2017;
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339 Effects of growth hormone-releasing hormone gene targeted ablation on ghrelin-induced feeding
Lucia Recinella,Sheila Leone,Claudio Ferrante,Annalisa Chiavaroli,Rugia Shohreh,Chiara Di Nisio,Michele Vacca,Giustino Orlando,Roberto Salvatori,Luigi Brunetti
Growth Hormone & IGF Research. 2017; 37: 40
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340 In vivo evaluation of antipyretic effects of some homeopathic ultra-high dilutions on Bakeræs yeast-induced fever on Similia principle
Saeed Ahmad,Tayyeba Rehman,Waheed Mumtaz Abbasi
Journal of Ayurveda and Integrative Medicine. 2017;
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341 Behavioural phenotype of histamine H4 receptor knockout mice: Focus on central neuronal functions
Maria Domenica Sanna,Carla Ghelardini,Robin L. Thurmond,Emanuela Masini,Nicoletta Galeotti
Neuropharmacology. 2017; 114: 48
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342 Effects of paclitaxel on the development of neuropathy and affective behaviors in the mouse
Wisam Toma,S. Lauren Kyte,Deniz Bagdas,Yasmin Alkhlaif,Shakir D. Alsharari,Aron H. Lichtman,Zhi-Jian Chen,Egidio Del Fabbro,John W. Bigbee,David A. Gewirtz,M. Imad Damaj
Neuropharmacology. 2017; 117: 305
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343 Silencing of the RNA-binding protein HuR attenuates hyperalgesia and motor disability in experimental autoimmune encephalomyelitis
Maria Domenica Sanna,Alessandro Quattrone,Nicoletta Galeotti
Neuropharmacology. 2017; 123: 116
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344 Activation of ERK/CREB pathway in noradrenergic neurons contributes to hypernociceptive phenotype in H4 receptor knockout mice after nerve injury
Maria Domenica Sanna,Tommaso Mello,Emanuela Masini,Nicoletta Galeotti
Neuropharmacology. 2017;
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345 Biphasic calcium phosphates bioceramics (HA/TCP): Concept, physicochemical properties and the impact of standardization of study protocols in biomaterials research
Mehdi Ebrahimi,Michael G. Botelho,Sergey V. Dorozhkin
Materials Science and Engineering: C. 2017; 71: 1293
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346 How do stocking density and straw provision affect fouling in conventionally housed slaughter pigs?
Mona Lilian Vestbjerg Larsen,Maja Bertelsen,Lene Juul Pedersen
Livestock Science. 2017; 205: 1
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347 Possible antifibrotic effect of GDC-0449 (Vismodegib), a hedgehog-pathway inhibitor, in mice model of Schistosoma –induced liver fibrosis
Abeer A. Elhenawy,Rehab H. Ashour,Nairmen Nabih,Naglaa M. Shalaby,Nirmeen Megahed
Parasitology International. 2017;
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348 The new HDAC1 inhibitor LG325 ameliorates neuropathic pain in a mouse model
Maria Domenica Sanna,Luca Guandalini,Maria Novella Romanelli,Nicoletta Galeotti
Pharmacology Biochemistry and Behavior. 2017;
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349 Anorexigenic effects induced by RVD-hemopressin(a) administration
Claudio Ferrante,Lucia Recinella,Sheila Leone,Annalisa Chiavaroli,Chiara Di Nisio,Sara Martinotti,Adriano Mollica,Giorgia Macedonio,Azzurra Stefanucci,Szabolcs Dvorácskó,Csaba Tömböly,Luciano De Petrocellis,Michele Vacca,Luigi Brunetti,Giustino Orlando
Pharmacological Reports. 2017; 69(6): 1402
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350 Emotional disorders induced by Hemopressin and RVD-hemopressin(a) administration in rats
Sheila Leone,Lucia Recinella,Annalisa Chiavaroli,Sara Martinotti,Claudio Ferrante,Adriano Mollica,Giorgia Macedonio,Azzurra Stefanucci,Szabolcs Dvorácskó,Csaba Tömböly,Luciano De Petrocellis,Michele Vacca,Luigi Brunetti,Giustino Orlando
Pharmacological Reports. 2017; 69(6): 1247
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351 A study of the prebiotic-like effects of tomato juice consumption in rats with diet-induced non-alcoholic fatty liver disease (NAFLD)
F. J. García-Alonso,R. González-Barrio,G. Martín-Pozuelo,N. Hidalgo,I. Navarro-González,D. Masuero,E. Soini,U. Vrhovsek,M. J. Periago
Food Funct.. 2017;
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352 Chemical characterization, antioxidant properties, anti-inflammatory activity and enzyme inhibition of Ipomoea batatas L. leaf extracts
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