Visha MG, Deepak Moses Ravindran, Balaji SK, and Lekha Ashokkumar Department of Periodontology, Sri Ramachandra Dental College and Hospital, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India Corresponding author(s): Deepak Moses Ravindran, Department of Periodontology, Sri Ramachandra Dental College and Hospital, Sri Ramachandra Institute of Higher Education and Research (Deemed to be University), No. 1 Ramachandra Nagar, Porur, Chennai, Tamil Nadu 600116, India. E-mail: deepak_perio@sriramachandra.edu.in DOI: 10.1177/0976500X241306178 Abstract Background Periodontal disease is a chronic inflammatory disease that activates the innate immune response. Activation of the TREM-1 signaling pathway promotes the synthesis of inflammatory cytokines like interleukin-1 beta (IL-1β), tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6) and…
Author: Zuhaib Ahmed
Akella Krishna Sowmya and Sunil Kumar Pandey Department of Pharmacology, Gayatri Vidya Parishad Institute of Health Care and Medical Technology, Visakhapatnam, Andhra Pradesh, India. Corresponding author(s): Akella Krishna Sowmya, Department of Pharmacology, Gayatri Vidya Parishad Institute of Health Care and Medical Technology, Visakhapatnam, Andhra Pradesh 530048, India. E-mail: sowmyakrishna0.0@gmail.com DOI: 10.1177/0976500X241305442 Abstract Background Mental health issues in children and adolescents are quite significant. Despite their impact, research on psychiatric disorders in these age groups is limited. This study aims to evaluate the prescription patterns of psychiatric medications and the prevalence of psychiatric disorders among children and adolescent age group patients. Objectives This study aims to evaluate the…
Mohammed Kanan1, Abdullah Almotairi2, Faisal Alrumaih3, Reem Hammad3, and Mohammed Almotairi1 1Department of Clinical Pharmacy, King Fahad Medical City, Riyadh, Saudi Arabia 2Department of Clinical Pharmacy, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia 3Department of Clinical Pharmacy, Northern Border University, Arar, Saudi Arabia Corresponding author(s): Mohammed Kanan, Department of Clinical Pharmacy, King Fahad Medical City, Riyadh 12211, Saudi Arabia. E-mail: ii_kanan101@outlook.com DOI: 10.1177/0976500X241303618 Abstract Background Bone marrow transplantation (BMT) is a crucial treatment for pediatric patients with various hematological, oncological, and genetic diseases. However, persistent thrombocytopenia (PT) post-transplantation poses a significant challenge, affecting recovery and prognosis. Objectives This study aimed to identify the clinical characteristics and risk…
Aashish Joshi1,2, Kailash Karande1, and Ravindra Gunaki3 1Department of Electronics & Telecommunication Engineering, SKN Sinhgad College of Engineering, Korti, Pandharpur, Solapur, Maharashtra, India 2Department of Electronics and Telecommunication Engineering, Karmayogi Institute of Technology Shelve, Pandharpur, Solapur, Maharashtra, India 3Orthopedics Department, KVV Krishna Institute of Medical Sciences Deemed University (Krishna Vishwa Vidyapeeth), Karad, Satara, Maharashtra, India Corresponding author(s): Aashish Joshi, Department of Electronics and Telecommunication Engineering, SKN Sinhgad College of Engineering, Korti, Pandharpur, Solapur, Maharashtra 413304, India. E-mail: ashu.joshi05@gmail.com DOI: 10.1177/0976500X241303572 Abstract Background Accidents are the major reasons causing hip bone fractures. These are due to reduced bone density due to aging effect which may cause fractures typically…
Ajay Gattani, Komal Khurade, Raakhi Tripathi, Rajmohan Seetharaman, and Sharmila Jalgaonkar Department of Pharmacology and Therapeutics, Seth G. S. Medical College & KEM Hospital, Parel, Mumbai, Maharashtra, India Corresponding author(s): Sharmila Jalgaonkar, Department of Pharmacology and Therapeutics, Seth G. S. Medical College & KEM Hospital, Parel, Mumbai, Maharashtra 400012, India. E-mail: sharmilajalgaonkar@kem.edu DOI: 10.1177/0976500X241299162 Abstract Background Animal models play a critical role in biomedical research, yet comprehensive data on the types and distribution of animals used in different research contexts are sparse. Objectives This study aims to provide a detailed analysis of small laboratory animals used in preclinical research, highlighting the types of animal species used, study types, and disease systems…
Patrick A. Kalona1, Uma Sundaresan2, Chellappandian Muthiah3, and Ariharasivakumar Ganesan4 1PT. Phytochemindo Reska, Bogor, Indonesia 2Department of Food Process Engineering, School of Bioengineering, SRM University, Kattankulathur, Tamil Nadu, India 3PG and Research Department of Botany, V.O.Chidambaram College, Thoothukodi, Tamil Nadu, India 4Department of Pharmacology, KMCH College of Pharmacy, Coimbatore, Tamil Nadu, India Corresponding author(s): Ariharasivakumar Ganesan, Department of Pharmacology, KMCH College of Pharmacy, Kovai Estate, Kalapatti Road, Coimbatore, Tamil Nadu 641048, India. E-mail: ariharakmchcology@gmail.com. DOI: 10.1177/0976500X241299159 Abstract Background Cyclophosphamide is one of the most extensively used chemotherapeutic drugs and is employed to treat several malignancies. Cyclophosphamide often comes with several unpleasant side effects. The primary negative consequence of cyclophosphamide…
Nitya Krishnasamy1, Ramya Ramadoss1, Kochli Channapa Niranjan2, Vikram S Amberkar3, Haris Chandra Sahoo4, and Poorna Devadoss5 1Department of Oral Biology, Saveetha Dental College & Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, India 2Department of Oral and Maxillofacial Pathology, SDM College of Dental Sciences, Shri Dharmasthala Manjunatheshwara University, Dharwad, Karnataka, India 3Department of Oral and Maxillofacial Pathology, College of Dental Sciences, Davangere, Karnataka, India 4Naturopathic Practitioner, Badarpur, New Delhi, India 5Thai Moogambigai Dental College and Hospital, Dr. MGR Educational and Research Institute, Chennai, Tamil Nadu Corresponding author(s): Ramya Ramadoss, Department of Oral Biology, Saveetha Dental College & Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu…
Aditya Kumar Bubna and Vinayak Viplav Department of Dermatology, Katihar Medical College, Katihar, Bihar, India Corresponding author(s): Aditya Kumar Bubna, Department of Dermatology, Katihar Medical College, Karim Bagh, Katihar 854106 Bihar, India. E-mail: zimbabwa21@gmail.com DOI: 10.1177/0976500X241303186 Abstract Background Apremilast is a phosphodiesterase-4 (PDE-4) inhibitor approved by the US-Food and Drug Administration (US-FDA) for the management of adult patients with plaque psoriasis (who are candidates for phototherapy/systemic therapy), moderate-to-severely active psoriatic arthritis and Behcet’s disease associated with oral ulcers. Objectives This review aims to summarize the current evidence for the off-label use of apremilast in various dermatological disorders. Methodology A comprehensive search of relevant literature was conducted…
Mohammed K. Alshammari1, Hind M. Al Osaimi2, Norah F. Alshehri1, Raneem F. Masoud3, Alaa O. Abdulaal4, and Bashair Z. Al Qaidi3 1Department of Clinical Pharmacy, King Fahad Medical City, Riyadh, Saudi Arabia 2Department of Pharmacy Services Administration, King Fahad Medical City, Riyadh Secondary Health Cluster, Riyadh, Saudi Arabia 3Department of Clinical Pharmacy, King Salman bin Abdulaziz Medical City, Ministry of Health Madinah, Madinah, Saudi Arabia 4Department of Pharmaceutical Care, Department of Clinical Pharmacy, King Salman bin Abdulaziz Medical City, Ministry of Health Madinah, Madinah, Saudi Arabia Corresponding author(s): Mohammed K. Alshammari, Department of Clinical Pharmacy, King Fahad Medical City, Riyadh 12211, Saudi Arabia. E-mail: mkaalshammari@kfmc.med.sa DOI: 10.1177/0976500X241303306 Abstract Background Pediatric wellbeing and health…
Harish Kumar, Seema Bansal, Rishabh Chaudhary, Wandeep Dagar, Neha Goyal, Khushboo Aggarwal, Sumeet Gupta, and Sunayna Choudhary M. M. College of Pharmacy, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, Haryana, India Corresponding author(s): Seema Bansal, M. M. College of Pharmacy, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, Haryana 133206, India. E-mail: 2006.seema@gmail.com Corresponding author(s): Sunayna Choudhary, M. M. College of Pharmacy, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, Haryana 133206, India. E-mail: sanachoudhary1988@gmail.com DOI: 10.1177/0976500X241303566 Abstract Background Oxidative stress is the primary factor responsible for the development of neuroinflammation and brain deficits. As aging occurs, the chances of oxidative stress increase due to lifestyle modification, environmental, and genetic factors. The brain is especially susceptible…