Journal of Pharmacology and Pharmacotherapeutics

REVIEW ARTICLE
Year
: 2021  |  Volume : 12  |  Issue : 3  |  Page : 107--109

2-deoxy-d-glucose: A ray of hope in covid pandemic


Priyotosh Banerjee, Indrani Devi Sarma, Dasgupta Himadri Sekhar, Dhriti Kumar Brahma, Melambha Surong 
 Department of Pharmacology, NEIGRIHMS, Shillong, Meghalaya, India

Correspondence Address:
Dhriti Kumar Brahma
Department of Pharmacology, NEIGRIHMS, Shillong - 793 018, Meghalaya
India

Coronavirus disease-19 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 is a respiratory tract infection that has already made a huge negative impact in global health situation. Transmission mainly occurs through droplets, and the virus is highly contagious. Mainly symptomatic treatments are given at present with some drugs for serious patients with unproven efficacy and safety. In this context, Institute of Nuclear Medicine and Allied Sciences, a research laboratory of Defence Research and Development Organization in collaboration with Dr. Reddy's Laboratories, Hyderabad, has introduced a new medicine named 2-Deoxy-d-glucose (2-DG) (which has been previously tried in cancer) for the treatment of seriously ill COVID patients with a target to reduce the oxygen demand. Clinical trials showed evidence that 2-DG effectively reduces oxygen requirement in seriously ill patients, and real-time polymerase chain reaction conversion is also faster. Recently, 2-DG is approved for the use in critically ill patients by the Drug Controller General of India in May 2021. The introduction of 2-DG brings a new hope in reducing the mortality in COVID patients.


How to cite this article:
Banerjee P, Sarma ID, Sekhar DH, Brahma DK, Surong M. 2-deoxy-d-glucose: A ray of hope in covid pandemic.J Pharmacol Pharmacother 2021;12:107-109


How to cite this URL:
Banerjee P, Sarma ID, Sekhar DH, Brahma DK, Surong M. 2-deoxy-d-glucose: A ray of hope in covid pandemic. J Pharmacol Pharmacother [serial online] 2021 [cited 2021 Nov 29 ];12:107-109
Available from: http://www.jpharmacol.com/article.asp?issn=0976-500X;year=2021;volume=12;issue=3;spage=107;epage=109;aulast=Banerjee;type=0