Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. BackgroundPulmonary hypertension (PH) is a disorder of the pulmonary blood vessels that is often accompanied by other clinical conditions, which can lead to complications in cardiovascular and respiratory diseases. The clinical outcome of patients with PH …Read Original Source

Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. BackgroundMedical students experience a heightened risk of depression and necessitate effective, low-side-effect interventions.PurposeThis study evaluates the efficacy of saffron in decreasing salivary cortisol levels and alleviating mild depressive …Read Original Source

Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. BackgroundImmunotherapy has wholly changed how cancer is treated by using the body’s immune system to eliminate cancer cells. Cancer vaccines, chimeric antigen receptor T-cell (CAR-T) treatments, and immune checkpoint inhibitors (ICIs) are at the …Read Original Source

Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. BackgroundHypertension is a worldwide health issue and an independent risk factor for cardiovascular disease. Endothelial dysfunction is an important mechanism for its pathogenesis, thus compromising vascular homeostasis and causing vascular remodeling. …Read Original Source

Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. BackgroundSurgical wound healing remains challenging in the clinical setting, bedeviled by infection, inflammation, and dysfunctional tissue regeneration. Present treatments rely on dressings and anti-biotics, whose bioavailability and site-specific …Read Original Source

Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. BackgroundSelective serotonin reuptake inhibitors (SSRIs), including fluoxetine and sertraline, are widely prescribed for depression due to their favorable safety profiles compared to older anti-depressants. However, these medications are associated with …Read Original Source

Visha MG, Deepak Moses Ravindran, Balaji SK, and Lekha Ashokkumar Department of Periodontology, Sri Ramachandra Dental College and Hospital, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India Corresponding author(s): Deepak Moses Ravindran, Department of Periodontology, Sri Ramachandra Dental College and Hospital, Sri Ramachandra Institute of Higher Education and Research (Deemed to be University),…

Akella Krishna Sowmya and Sunil Kumar Pandey Department of Pharmacology, Gayatri Vidya Parishad Institute of Health Care and Medical Technology, Visakhapatnam, Andhra Pradesh, India. Corresponding author(s): Akella Krishna Sowmya, Department of Pharmacology, Gayatri Vidya Parishad Institute of Health Care and Medical Technology, Visakhapatnam, Andhra Pradesh 530048, India. E-mail: sowmyakrishna0.0@gmail.com DOI: 10.1177/0976500X241305442 Abstract Background Mental health issues in…