Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. BackgroundPeriodontitis, an inflammatory disease, is caused by oral biofilm, and several risk factors propagate it. Smoking is a significant risk factor that increases the severity of the disease. ArylamineN-acetyltransferase 2 (NAT2) enzyme present in …Read Original Source

Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. Aim/BackgroundAccurate staging of lung cancer is critical for treatment planning and prognosis. Traditional methods typically rely on binary classification and manual analysis of computed tomography (CT) scans, limiting diagnostic precision and …Read Original Source

Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. BackgroundAcneiform eruption is a dermatological condition resembling acne vulgaris, with a similar clinical presentation that is often difficult to differentiate. Several medications like corticosteroids, anti-convulsants, anti-psychotics, anti-…Read Original Source

Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. BackgroundLeopoldia comosais a traditional Mediterranean plant with medicinal and nutritional value. Despite its long history of use, scientific exploration remains limited.PurposeThis study aimed to provide the first comprehensive bibliometric analysis …Read Original Source

Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. BackgroundSeveral therapies are available for psoriasis, including oral, parenteral, and phototherapy. However, these treatments present various drawbacks, like mucosal ulceration, stomatitis, bioavailability issues, patient compliance challenges, and …Read Original Source

Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. Purpose/BackgroundThis study aimed to isolate, purify, and characterize a novel bacteriocin produced byLactobacillus caseistrain GO3, isolated from goat milk. Bacteriocins are promising natural antimicrobial agents with potential applications in food …Read Original Source

Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. BackgroundEpilepsy affects around 70 million people worldwide, with a higher prevalence in developing countries like Malaysia. Antiepileptic drugs (AEDs) such as carbamazepine, phenobarbitone, valproic acid, and phenytoin are essential for managing …Read Original Source

Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. BackgroundUbrogepant is a first-generation gepant-class drug approved for the oral treatment of migraine.PurposeThis work aimed at developing an intranasal gel consisting of ubrogepant nanoparticles (NPs), with the aim of improving its therapeutic …Read Original Source