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Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. BackgroundHand hygiene is the key to prevent spread of infections in any health care setting. It is vital to understand and assess health care students knowledge and understanding towards hand hygiene so that effective infection control can be ensured….Read Original Source

Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. BackgroundOpioids have been an integral part of pain management for many years. With the increasing global burden of opioid dependence, the development of non-opioid therapies provides a new framework for pain management. Suzetrigine is a stepping stone …Read Original Source

Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. BackgroundDoxorubicin (DX)-induced cardiotoxicity involves dose- and time-dependent myocardial injury driven by oxidative stress, mitochondrial dysfunction, and disrupted topoisomerase IIβ signaling, leading to progressive left ventricular dysfunction and …Read Original Source

Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. BackgroundThe utilisation of vasoconstrictors like clonidine with local anaesthetics during subarachnoid blockade is a well-established practice.PurposeThis study aims to compare the effects of oral clonidine premedication versus placebo on the onset and …Read Original Source

Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. BackgroundCancer is a complex condition defined by the uncontrolled growth and proliferation of cells. Brain neoplasms, both primary and secondary, present a rising global health burden. Newer classification integrates key molecular markers; IDH mutation, …Read Original Source

Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. BackgroundIn Serbia, as well as worldwide, clinical trials are a significant and unavoidable part of the development of new medicines. There is limited research on prospective risk management in clinical trials in Serbia, underscoring the need for …Read Original Source

Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. A case of colchicine overdose of 27 mg, or 0.27 mg/kg (weight 99.8 kg), is reported to assess the potential symptoms seen with this type of toxicity and analyze a prospective treatment for successful outcomes. A 74-year-old man unintentionally ingested …Read Original Source

Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. BackgroundAutoimmune and inflammatory diseases, such as rheumatoid arthritis, multiple sclerosis, inflammatory bowel disease, and psoriasis, are typified by immune dysregulation resulting in chronic inflammation and progressive tissue injury. Standard …Read Original Source

Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. BackgroundSickle cell anemia is a monogenic hemoglobinopathy caused by a mutation in the β-globin gene (hemoglobin subunit beta, HBB), leading to the production of hemoglobin S (HbS). Under deoxygenated conditions, HbS polymerizes abnormally, causing red …Read Original Source

Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. BackgroundNoni (Morinda citrifolia Linn.) fruit has a long history of traditional use for treating several health conditions, including symptoms of major depression and anxiety.PurposeThis study focused on evaluating the therapeutic potential of the …Read Original Source