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Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. BackgroundMedical students experience a heightened risk of depression and necessitate effective, low-side-effect interventions.PurposeThis study evaluates the efficacy of saffron in decreasing salivary cortisol levels and alleviating mild depressive …Read Original Source

Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. BackgroundHypertension is a worldwide health issue and an independent risk factor for cardiovascular disease. Endothelial dysfunction is an important mechanism for its pathogenesis, thus compromising vascular homeostasis and causing vascular remodeling. …Read Original Source

Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. BackgroundImmunotherapy has wholly changed how cancer is treated by using the body’s immune system to eliminate cancer cells. Cancer vaccines, chimeric antigen receptor T-cell (CAR-T) treatments, and immune checkpoint inhibitors (ICIs) are at the …Read Original Source

Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. BackgroundSurgical wound healing remains challenging in the clinical setting, bedeviled by infection, inflammation, and dysfunctional tissue regeneration. Present treatments rely on dressings and anti-biotics, whose bioavailability and site-specific …Read Original Source

Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. BackgroundSelective serotonin reuptake inhibitors (SSRIs), including fluoxetine and sertraline, are widely prescribed for depression due to their favorable safety profiles compared to older anti-depressants. However, these medications are associated with …Read Original Source

Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. BackgroundDrug–drug interactions (DDIs) are a significant concern among cardiac inpatients, potentially impacting therapeutic outcomes and patient safety. Early identification and management of potential DDIs are crucial in preventing adverse events, …Read Original Source

Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. BackgroundIntraoperative hypothermia is a common complication in elderly patients undergoing joint replacement surgery that can lead to adverse outcomes.PurposeThis study aimed to analyze the pertinent risk factors influencing intraoperative hypothermia …Read Original Source

Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. BackgroundThe brain, through the sensory action of neurons situated in the hypothalamus and brainstem, plays a pivotal role in the homeostatic regulation of glucose metabolism. The brain senses changes in nutrients and hormones. It triggers negative …Read Original Source

Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. The increasing pressure on academic faculty to balance teaching, research productivity, publication impact, and ethical integrity amidst stringent institutional and global academic expectations poses significant challenges. The role of academic faculty …Read Original Source

Journal of Pharmacology and Pharmacotherapeutics, Ahead of Print. Read Original Source